Gasometría arterial y retinopatía en prematuros de muy bajo peso al nacer.: Arterial blood gas and retinopathy in very low birth weight premature infants.

• Autores: Huamán-Rodríguez, Martina Rosaria, Zavaleta-Gutierrez, Francisca Elena, Tapia-Zerpa, Jorge Luis, Sánchez-Reyna, Víctor Andrés, Aguilar-Urbina, Edi William
• Formato: artículo
• Fecha de Publicación: 2023
• Institución: Universidad Nacional de Trujillo
• Repositorio: Revistas - Universidad Nacional de Trujillo
• Lenguaje: español
• OAI Identifier: oai:ojs.revistas.unitru.edu.pe:article/5106
• Enlace del recurso: https://revistas.unitru.edu.pe/index.php/RMT/article/view/5106
• Nivel de acceso: acceso abierto
• Materia: Retinopathy of Prematurity; preterm infant; hyperoxia; hypoxia; acidosis; Retinopatía de la prematuridad; pretérmino; hiperoxia; hipoxia

Objetive: To determine if arterial blood gas alterations are associated with retinopathy in very low birth weight premature infants. Methods: Observational, analytical, retrospective and longitudinal study, design of cases and controls. Medical records of premature infants born at the Hospital Belén de Trujillo (2013-2017) were reviewed. The association between each alteration in arterial blood gas and ROP was evaluated with the chi-square test and multivariate logistic regression analysis was used to adjust for the effect of the remaining alterations. Results: There were 49 cases and 147 controls. Hyperoxemia, gestational age <28 weeks, birth weight <1 000 grams, resuscitation, intubation, apgar <7 at minute, and mechanical ventilation were associated with ROP (p <0,05). Cesarean delivery was a protective factor for ROP (p <0,05). In the multivariate analysis, the only significant coefficient associated with ROP was gestational age <28 weeks with OR = 7,34. Conclusion: Hyperoxemia is the gasometric alteration associated with ROP, but the factor that significantly influences the estimation of ROP is gestational age <28 weeks, which increases the risk 7,34 times.