Use of antihypertensives as a protective factor for non-traumatic hip fracture

• Autor: Marinovich-Milenka, Nuñez
• Formato: artículo
• Fecha de Publicación: 2023
• Institución: Universidad de Huánuco
• Repositorio: Revistas - Universidad de Huánuco
• Lenguaje: español
• OAI Identifier: oai:ojs2.localhost:article/483
• Enlace del recurso: http://revistas.udh.edu.pe/index.php/RPCS/article/view/423e
• Nivel de acceso: acceso abierto
• Materia: antihipertensivos; disminución del riesgo; fractura de cadera; no traumática; antihypertensives; risk reduction; nontraumatic; fracture

Objective. To determine whether the use of antihypertensives is associated with reduced risk of nontraumatic hip fracture in patients at Hospital Belén de Trujillo, 2017-2022. Methods. A retrospective, analytical, cross-sectional study was conducted. According to the selection criteria, 160 adult patients were included and divided into 2 groups: with or without nontraumatic hip fracture; then, the prevalence ratio and the chi-square statistical test were applied. Results. Mean age and frequency of osteoporosis were significantly higher in the group of patients with hip fracture (p < 0.05). The consumption of thiazide antihypertensives was a protective factor for non-traumatic hip fracture, with a prevalence ratio of 0.29, which was significant (p < 0.05). The use of beta-blockers was a protective factor for non-traumatic hip fracture, with a prevalence ratio of 0.30, which was significant (p < 0.05). The use of ARBs was a protective factor for non-traumatic hip fracture, with a prevalence ratio of 0.26, which was significant (p < 0.05). The consumption of ACEI was not a protective factor for non-traumatic hip fracture, with a prevalence ratio of 1.11, which was not significant (p > 0.05). Conclusions. The use of antihypertensives is associated with decreased risk of nontraumatic hip fracture in patients at Hospital Belén de Trujillo, 2017-2022 (level of evidence III-B)