HYPERGLYCEMIA AND PREGNANCY
Descripción del Articulo
The HAPO study encompassed 25,505 unique pregnancies across 9 countries, which underwent a 2-hour Oral Glucose Tolerance Test (OGTT) with 75 g of glucose between weeks 24 to 32 of gestation. In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) reported that the...
Autor: | |
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Formato: | artículo |
Fecha de Publicación: | 2024 |
Institución: | Instituto Nacional Materno Perinatal |
Repositorio: | Revista Peruana de Investigación Materno Perinatal |
Lenguaje: | español |
OAI Identifier: | oai:ojs.www.fracturae.com:article/331 |
Enlace del recurso: | https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/331 |
Nivel de acceso: | acceso abierto |
Materia: | Glicemia materna Diabetes gestacional Macrosomia fetal Diabetes mellitus Materna glycemia Gestational Diabetes Fetal macrosomia diabetes mellitus |
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Revista Peruana de Investigación Materno Perinatal |
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dc.title.none.fl_str_mv |
HYPERGLYCEMIA AND PREGNANCY HIPERGLICEMIA Y EMBARAZO |
title |
HYPERGLYCEMIA AND PREGNANCY |
spellingShingle |
HYPERGLYCEMIA AND PREGNANCY Pacora Portella, Percy Glicemia materna Diabetes gestacional Macrosomia fetal Diabetes mellitus Materna glycemia Gestational Diabetes Fetal macrosomia diabetes mellitus |
title_short |
HYPERGLYCEMIA AND PREGNANCY |
title_full |
HYPERGLYCEMIA AND PREGNANCY |
title_fullStr |
HYPERGLYCEMIA AND PREGNANCY |
title_full_unstemmed |
HYPERGLYCEMIA AND PREGNANCY |
title_sort |
HYPERGLYCEMIA AND PREGNANCY |
dc.creator.none.fl_str_mv |
Pacora Portella, Percy |
author |
Pacora Portella, Percy |
author_facet |
Pacora Portella, Percy |
author_role |
author |
dc.subject.none.fl_str_mv |
Glicemia materna Diabetes gestacional Macrosomia fetal Diabetes mellitus Materna glycemia Gestational Diabetes Fetal macrosomia diabetes mellitus |
topic |
Glicemia materna Diabetes gestacional Macrosomia fetal Diabetes mellitus Materna glycemia Gestational Diabetes Fetal macrosomia diabetes mellitus |
description |
The HAPO study encompassed 25,505 unique pregnancies across 9 countries, which underwent a 2-hour Oral Glucose Tolerance Test (OGTT) with 75 g of glucose between weeks 24 to 32 of gestation. In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) reported that the diagnosis of hyperglycemia in pregnancy could be established using fasting values, and 1 and 2 hours post OGTT levels associated with a 1.75 times increased risk above the average of adverse effects found in the HAPO study. These levels corresponded to fasting blood sugar ≥ 92 mg/dl, 1-hour blood sugar ≥ 180 mg/dl, and 2-hour blood sugar ≥ 153 mg/dl. Although the OGTT in the HAPO study was conducted from week 24 to 32 of pregnancy, the World Health Organization in 2013 recommended using these values for the diagnosis of hyperglycemia in pregnancy outside of this gestational period, a recommendation that was later endorsed by the International Federation of Gynecology and Obstetrics (FIGO) in 2015. However, a retrospective cohort study of 6,035 pregnancies in Peruvian women who underwent OGTT between weeks 7 to 41 of pregnancy demonstrated that several factors including the number of fetuses, gestational age, maternal age over 24 years, body mass index over 24.9 kg/m2, number of prior births, the presence of poor reproductive history, and personal or family history of cardiovascular risk diseases affected maternal blood sugar levels during pregnancy. Consequently, the Lima criteria were established, corresponding to blood sugar levels ≥ 95th percentile in 650 healthy, nulliparous women aged 18 to 24 years, with singleton pregnancies and without factors affecting maternal blood sugar. This criterion demonstrated greater sensitivity and accuracy in identifying pregnant women who underwent primary cesarean section, neonates with a weight over 4 kg, preterm neonates, neonates large for gestational age, and neonatal sepsis compared to the IADPSG criteria. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-04-19 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/331 10.33421/inmp.2023331 |
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https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/331 |
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10.33421/inmp.2023331 |
dc.language.none.fl_str_mv |
spa |
language |
spa |
dc.relation.none.fl_str_mv |
https://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/331/373 |
dc.rights.none.fl_str_mv |
Derechos de autor 2024 Revista Peruana de Investigación Materno Perinatal https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Derechos de autor 2024 Revista Peruana de Investigación Materno Perinatal https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Nacional Materno Perinatal (INMP), Lima - Perú. |
publisher.none.fl_str_mv |
Instituto Nacional Materno Perinatal (INMP), Lima - Perú. |
dc.source.none.fl_str_mv |
Revista Peruana de Investigación Materno Perinatal; Vol 12 No 4 (2023): Revista Peruana de Investigación Materno Perinatal; 27-41 Revista Peruana de Investigación Materno Perinatal; Vol. 12 Núm. 4 (2023): Revista Peruana de Investigación Materno Perinatal; 27-41 2663-113X 2305-3887 10.33421/124 reponame:Revista Peruana de Investigación Materno Perinatal instname:Instituto Nacional Materno Perinatal instacron:INMP |
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Instituto Nacional Materno Perinatal |
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INMP |
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INMP |
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Revista Peruana de Investigación Materno Perinatal |
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Revista Peruana de Investigación Materno Perinatal |
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spelling |
HYPERGLYCEMIA AND PREGNANCYHIPERGLICEMIA Y EMBARAZOPacora Portella, PercyGlicemia maternaDiabetes gestacionalMacrosomia fetalDiabetes mellitusMaterna glycemiaGestational DiabetesFetal macrosomiadiabetes mellitusThe HAPO study encompassed 25,505 unique pregnancies across 9 countries, which underwent a 2-hour Oral Glucose Tolerance Test (OGTT) with 75 g of glucose between weeks 24 to 32 of gestation. In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) reported that the diagnosis of hyperglycemia in pregnancy could be established using fasting values, and 1 and 2 hours post OGTT levels associated with a 1.75 times increased risk above the average of adverse effects found in the HAPO study. These levels corresponded to fasting blood sugar ≥ 92 mg/dl, 1-hour blood sugar ≥ 180 mg/dl, and 2-hour blood sugar ≥ 153 mg/dl. Although the OGTT in the HAPO study was conducted from week 24 to 32 of pregnancy, the World Health Organization in 2013 recommended using these values for the diagnosis of hyperglycemia in pregnancy outside of this gestational period, a recommendation that was later endorsed by the International Federation of Gynecology and Obstetrics (FIGO) in 2015. However, a retrospective cohort study of 6,035 pregnancies in Peruvian women who underwent OGTT between weeks 7 to 41 of pregnancy demonstrated that several factors including the number of fetuses, gestational age, maternal age over 24 years, body mass index over 24.9 kg/m2, number of prior births, the presence of poor reproductive history, and personal or family history of cardiovascular risk diseases affected maternal blood sugar levels during pregnancy. Consequently, the Lima criteria were established, corresponding to blood sugar levels ≥ 95th percentile in 650 healthy, nulliparous women aged 18 to 24 years, with singleton pregnancies and without factors affecting maternal blood sugar. This criterion demonstrated greater sensitivity and accuracy in identifying pregnant women who underwent primary cesarean section, neonates with a weight over 4 kg, preterm neonates, neonates large for gestational age, and neonatal sepsis compared to the IADPSG criteria.El estudio HAPO incluyó 25 505 embarazos únicos en 9 países que se sometieron a una prueba de tolerancia oral a la glucosa de 2 horas con 75 g de glucosa (PTOG) en semana 24 a 32 de gestación. En el 2010, el Grupo Internacional de Asociaciones del estudio de la diabetes y el embarazo (IADPSG) reportó que el diagnóstico de hiperglicemia en el embarazo podía establecerse empleando los valores en ayunas, 1 y 2 horas post PTOG asociados a 1.75 veces mayor riesgo sobre la media de los efectos adversos del estudio HAPO, los cuales correspondieron a glicemia en ayunas ≥ 92 mg/dl, glicemia 1 hora ≥ 180 mg/dL y glicemia 2 horas ≥ 153 mg/dl. Aunque la PTOG en el estudio HAPO se realizó desde la semana 24 a 32 de embarazo, la Organización Mundial de la Salud en el 2013 recomendó emplear estos valores para diagnóstico de la hiperglicemia en el embarazo fuera de ese periodo del embarazo y ha sido respaldada por la Federación Internacional de Asociaciones de Ginecología y Obstetricia (FIGO) en 2015. Sin embargo, el estudio de una cohorte retrospectiva de 6 035 embarazos de mujeres peruanas sometidas a PTOG durante semana 7 a 41 del embarazo demostró que el número de fetos, el tiempo del embarazo, edad materna > 24 años, índice de masa corporal > 24.9 kg/m2, número de partos previos, presencia de mala historia reproductiva, historia personal y/o familiar de enfermedad con riesgo cardiovascular alteraban la concentración de glicemia materna en el embarazo. En consecuencia, se estableció el criterio Lima, el cual corresponde al valor de glicemia ≥ percentil 95 en 650 mujeres sanas, nulíparas, de 18 a 24 años, con embarazos simples sin la presencia de factores que afectaran la glicemia materna. Este criterio demostró mayor sensibilidad y certeza para identificar a las gestantes que tuvieron cesárea primaria, neonatos con peso mayor de 4 kg, neonato prematuro, neonato grande para la gestación y sepsis neonatal comparado con el criterio de la IADPSG.Instituto Nacional Materno Perinatal (INMP), Lima - Perú.2024-04-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/33110.33421/inmp.2023331Revista Peruana de Investigación Materno Perinatal; Vol 12 No 4 (2023): Revista Peruana de Investigación Materno Perinatal; 27-41Revista Peruana de Investigación Materno Perinatal; Vol. 12 Núm. 4 (2023): Revista Peruana de Investigación Materno Perinatal; 27-412663-113X2305-388710.33421/124reponame:Revista Peruana de Investigación Materno Perinatalinstname:Instituto Nacional Materno Perinatalinstacron:INMPspahttps://investigacionmaternoperinatal.inmp.gob.pe/index.php/rpinmp/article/view/331/373Derechos de autor 2024 Revista Peruana de Investigación Materno Perinatalhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:ojs.www.fracturae.com:article/3312024-04-19T19:23:25Z |
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13.882472 |
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La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).