Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients

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The purpose of the present study is to establish the effect of the yacon tuber and leaf (Smallantus Sonchifolius) on the levels of the seric glucose and glycosylated hemoglobin with the consumption of an adlibitum diet. A blind, simple and experimental field-controlled trial was carried out for a pe...

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Detalles Bibliográficos
Autores: Alfaro Ludeña, Clyff, Ugarte Rejavinsky, Karim, Belsuzarri Padilla, Iván
Formato: artículo
Fecha de Publicación:2022
Institución:Universidad de San Martín de Porres
Repositorio:Horizonte médico
Lenguaje:español
OAI Identifier:oai:horizontemedico.usmp.edu.pe:article/2022
Enlace del recurso:https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/2022
Nivel de acceso:acceso abierto
Materia:Yacon
Hemoglobina glicosilada
Glucosa sérica
Diabetes mellitus
Glycosylated hemoglobin
Seric glucose
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oai_identifier_str oai:horizontemedico.usmp.edu.pe:article/2022
network_acronym_str REVHM
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dc.title.none.fl_str_mv Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
Efecto normoglicemiante del tubérculo y la hoja del yacón (smallantus sonchifolius) en paciente diabéticos Tipo 2
title Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
spellingShingle Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
Alfaro Ludeña, Clyff
Yacon
Hemoglobina glicosilada
Glucosa sérica
Diabetes mellitus
Yacon
Glycosylated hemoglobin
Seric glucose
Diabetes mellitus
title_short Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
title_full Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
title_fullStr Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
title_full_unstemmed Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
title_sort Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patients
dc.creator.none.fl_str_mv Alfaro Ludeña, Clyff
Ugarte Rejavinsky, Karim
Belsuzarri Padilla, Iván
author Alfaro Ludeña, Clyff
author_facet Alfaro Ludeña, Clyff
Ugarte Rejavinsky, Karim
Belsuzarri Padilla, Iván
author_role author
author2 Ugarte Rejavinsky, Karim
Belsuzarri Padilla, Iván
author2_role author
author
dc.subject.none.fl_str_mv Yacon
Hemoglobina glicosilada
Glucosa sérica
Diabetes mellitus
Yacon
Glycosylated hemoglobin
Seric glucose
Diabetes mellitus
topic Yacon
Hemoglobina glicosilada
Glucosa sérica
Diabetes mellitus
Yacon
Glycosylated hemoglobin
Seric glucose
Diabetes mellitus
description The purpose of the present study is to establish the effect of the yacon tuber and leaf (Smallantus Sonchifolius) on the levels of the seric glucose and glycosylated hemoglobin with the consumption of an adlibitum diet. A blind, simple and experimental field-controlled trial was carried out for a period of 90 days in 30 subjects, in an age range from 26 to 90, who were diagnosed with Type 2 Diabetes Mellitus with no control despite the pharmacological treatment. The subjects were divided into 3 groups; the first group received 500g per day of fresh yacon fruit; the second group received freeze-dried yacon equivalent to 500 g per day of the fresh fruit, and the third group received yacon leaves tea bags (each tea bag containing the equivalent to 1 g of yacon leaves), which were taken three times a day.Regarding the glycosylated hemoglobin, the administration of the fruit, the tea bags and the freeze-dried yacon reduced an average of 1.98%, 1.84% and 1.14%, correspondingly, in each group. In the seric glucose we could observe a considerable drop in the fourth week in the three groups. The largest drop happened in the group that received the yacon tea bags and the lowest drop in the group that received the yacon fruit.We can conclude that the yacon, in its different presentations, produce a decrease of the seric glucose without reaching the normal values. It was also noticed that the changes in the concentration of the seric glu cose did not show a significant difference among the age groups nor in repeated measures of seric glucose among weeks nor in gender. A significant decrease of the final glycosylated hemoglobin regarding the basal was also shown in all the groups, finding a marked decrease in the group that received fresh yacon fruit.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-18
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/2022
10.24265/horizmed.2004.v4n1.04
url https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/2022
identifier_str_mv 10.24265/horizmed.2004.v4n1.04
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/2022/1244
dc.rights.none.fl_str_mv Derechos de autor 2022 Horizonte Médico (Lima)
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2022 Horizonte Médico (Lima)
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad de San Martín de Porres. Facultad de Medicina Humana
publisher.none.fl_str_mv Universidad de San Martín de Porres. Facultad de Medicina Humana
dc.source.none.fl_str_mv Horizonte Médico (Lima); Vol. 4 No. 1 (2004): January - June; 54-65
Horizonte Médico (Lima); Vol. 4 Núm. 1 (2004): Enero - Junio; 54-65
Horizonte Médico (Lima); v. 4 n. 1 (2004): Enero - Junio; 54-65
2227-3530
1727-558X
reponame:Horizonte médico
instname:Universidad de San Martín de Porres
instacron:USMP
instname_str Universidad de San Martín de Porres
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spelling Normoglycemic effect of the tuber and the yacón leaf (smallantus sonchifolius) in type 2 diabetic patientsEfecto normoglicemiante del tubérculo y la hoja del yacón (smallantus sonchifolius) en paciente diabéticos Tipo 2Alfaro Ludeña, ClyffUgarte Rejavinsky, KarimBelsuzarri Padilla, IvánYaconHemoglobina glicosiladaGlucosa séricaDiabetes mellitusYaconGlycosylated hemoglobinSeric glucoseDiabetes mellitusThe purpose of the present study is to establish the effect of the yacon tuber and leaf (Smallantus Sonchifolius) on the levels of the seric glucose and glycosylated hemoglobin with the consumption of an adlibitum diet. A blind, simple and experimental field-controlled trial was carried out for a period of 90 days in 30 subjects, in an age range from 26 to 90, who were diagnosed with Type 2 Diabetes Mellitus with no control despite the pharmacological treatment. The subjects were divided into 3 groups; the first group received 500g per day of fresh yacon fruit; the second group received freeze-dried yacon equivalent to 500 g per day of the fresh fruit, and the third group received yacon leaves tea bags (each tea bag containing the equivalent to 1 g of yacon leaves), which were taken three times a day.Regarding the glycosylated hemoglobin, the administration of the fruit, the tea bags and the freeze-dried yacon reduced an average of 1.98%, 1.84% and 1.14%, correspondingly, in each group. In the seric glucose we could observe a considerable drop in the fourth week in the three groups. The largest drop happened in the group that received the yacon tea bags and the lowest drop in the group that received the yacon fruit.We can conclude that the yacon, in its different presentations, produce a decrease of the seric glucose without reaching the normal values. It was also noticed that the changes in the concentration of the seric glu cose did not show a significant difference among the age groups nor in repeated measures of seric glucose among weeks nor in gender. A significant decrease of the final glycosylated hemoglobin regarding the basal was also shown in all the groups, finding a marked decrease in the group that received fresh yacon fruit.El presente estudio tiene como propósito establecer el efecto del tubérculo y hoja de yacón (smallantus sonchifolius) sobre los niveles de glucosa sérica y hemoglobina glicosilada con el consumo de una dieta ad libitum. Se realizó durante 90 días un ensayo experimental simple ciego controlado a nivel de campo en 30 sujetos entre los 26 y 90 años, con diagnóstico de diabetes mellitus tipo 2 no controlada a pesar del tratamiento farmacológico, dividiéndolos en tres grupos: al primer grupo se administro 500g/día de fruto fresco de yacón, al segundo grupo liofilizado de yacón equivalente a 500g/día del fruto fresco y al tercer grupo se le proporcionó bolsitas filtrantes de hoja de yacón (cada bolsita filtrante equivalente a lg de hoja), tomando tres infusiones al día.Con respecto a la hemoglobina glicosilada, la administración de fruto, filtrante y liofilizado disminuyó en promedio de 1.98%, 1.84 % y 1.14%, respectivamente, para cada grupo. En la glucosa sérica se apreció una baja considerable de la misma a la cuarta semana en los tres grupos teniendo mayor disminución el grupo con yacon filtrante y la menor disminución el grupo con fruto fresco.Podemos concluir que el yacón, en sus diferentes presentaciones produce disminución de la glucosa sérica sin llegar a valores normales, observando que los cambios en la concentración de glucosa sérica no evidenciaron diferencia significativa entre grupos etáreos ni en medidas repetidas de glucosa sérica entre semanas ni en género. También se evidenció una disminución significativa de la hemoglobina glicosilada final con respecto a la basal en todos los grupos, encontrándose disminución marcada en el grupo al que se le administró tubérculo fresco de yacon.Universidad de San Martín de Porres. Facultad de Medicina Humana2022-08-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/202210.24265/horizmed.2004.v4n1.04Horizonte Médico (Lima); Vol. 4 No. 1 (2004): January - June; 54-65Horizonte Médico (Lima); Vol. 4 Núm. 1 (2004): Enero - Junio; 54-65Horizonte Médico (Lima); v. 4 n. 1 (2004): Enero - Junio; 54-652227-35301727-558Xreponame:Horizonte médicoinstname:Universidad de San Martín de Porresinstacron:USMPspahttps://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/2022/1244Derechos de autor 2022 Horizonte Médico (Lima)https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:horizontemedico.usmp.edu.pe:article/20222022-08-18T03:52:34Z
score 13.95948
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