Association between type 2 diabetes mellitus and mortality in older adults with cardiovascular disease

• Autores: Huamán Macha, Verónica, Herrera Pandal, Alesandra, Runzer-Colmenares, Fernando M., Parodi, José F.
• Formato: artículo
• Fecha de Publicación: 2020
• Institución: Universidad de San Martín de Porres
• Repositorio: Horizonte médico
• Lenguaje: español
• OAI Identifier: oai:horizontemedico.usmp.edu.pe:article/1236
• Enlace del recurso: https://www.horizontemedico.usmp.edu.pe/index.php/horizontemed/article/view/1236
• Nivel de acceso: acceso abierto
• Materia: Diabetes mellitus; Mortalidad; Enfermedades cardiovasculares; Anciano; Geriatría; Mortality; Cardiovascular diseases; Aged; Geriatrics

Objective: To determine the association between mortality and type 2 diabetes mellitus (T2DM) in older adults with cardiovascular disease by adjusting a T2DM model with glycated hemoglobin (HbA1c). Materials and methods: A retrospective cohort study conducted with a secondary database analysis of the original article entitled “Prevalence and Factors Associated with Frailty Among Peruvian Older Adults.” No sample size calculation was performed because the research used the data from the participants who met the inclusion criteria. Results: Older adults with T2DM have 10 % more risk of mortality than those who do not have T2DM. The highest frequency of mortality occurred in men. The greater the number of comorbidities, the higher the risk of mortality. After applying the Cox proportional hazards model to the research, the most significant risk factors for mortality were frailty and the number comorbidities. Conclusions: T2DM was a risk factor for mortality in older adults with cardiovascular disease in all the models. Additionally, there were other important variables whose impact was directly proportional to the mortality rate in our population and statistically stood out, such as the number of comorbidities and frailty, while the history of tobacco consumption was not significant.