Antimicrobial therapy in severe infections

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Sepsis is considered a public health problem because severe infections still are a major cause of death worldwide. Within the comprehensive management of the patient with severe sepsis or septic shock, the early administration of an appropriate antimicrobial regimen is one of the key strategies for...

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Detalles Bibliográficos
Autor: Bisso Andrade, Aland
Formato: artículo
Fecha de Publicación:2011
Institución:Colegio Médico del Perú
Repositorio:Acta Médica Peruana
Lenguaje:español
OAI Identifier:oai:amp.cmp.org.pe:article/1081
Enlace del recurso:https://amp.cmp.org.pe/index.php/AMP/article/view/1081
Nivel de acceso:acceso abierto
Materia:Antibiótico
bacteriemia
agentes antifúngicos
candidemia
sepsis
shock séptico
Anti-Bacterial Agents
bacteremia
Antifungal Agents
shock septic
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spelling Antimicrobial therapy in severe infectionsAntibioticoterapia en las infecciones gravesBisso Andrade, Aland Antibióticobacteriemiaagentes antifúngicoscandidemiasepsisshock sépticoAnti-Bacterial AgentsbacteremiaAntifungal Agentscandidemiasepsisshock septicSepsis is considered a public health problem because severe infections still are a major cause of death worldwide. Within the comprehensive management of the patient with severe sepsis or septic shock, the early administration of an appropriate antimicrobial regimen is one of the key strategies for survival and for reducing morbidity and mortality. In this review, we describe the antimicrobial therapy for the following conditions: severe pneumonia, urosepsis, intra-abdominal infections, serious skin and soft tissue infections, bacterial meningitis, fungal sepsis, venous catheter-related infections, and sepsis of undetermined origin. It is necessary for physicians who take care of patients with serious infections, that they must know not only the clinical manifestations of each process, but also their epidemiological characteristics, local bacterial prevalence, resistance patterns and pharmacology of available antimicrobial agents in order to make the best decisions. Both guidelines and systematic reviews are fundamental tools for the management of serious infections.La sepsis se considera un problema de salud pública debido a que las infecciones graves aún constituyen una causa importante de muerte en todo el mundo. Dentro del manejo integral del paciente en estado de sepsis grave o en shock séptico, la administración temprana de un régimen antibiótico adecuado, constituye una de las estrategias fundamentales para la supervivencia y disminución de la morbimortalidad. En esta revisión se presenta el manejo antibiótico de las siguientes entidades: neumonía grave, urosepsis, infecciones intra-abdominales, infecciones graves de la piel y partes blandas, meningitis bacteriana, sepsis fungal, infección relacionada al catéter venoso y sepsis de origen no determinado. Es necesario que los médicos que tratan infecciones graves, conozcan no solo las manifestaciones clínicas de cada proceso, sino también sus características epidemiológicas, prevalencia bacteriana local, patrones de resistencia y la farmacología de los antibióticos disponibles, a fin de tomar la mejor decisión. Las guías y las revisiones sistémicas son herramientas fundamentales para el manejo de las infecciones graves.Colegio Médico del Perú2011-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://amp.cmp.org.pe/index.php/AMP/article/view/1081ACTA MEDICA PERUANA; Vol. 28 No. 1 (2011); 27-38ACTA MEDICA PERUANA; Vol. 28 Núm. 1 (2011); 27-381728-59171018-8800reponame:Acta Médica Peruanainstname:Colegio Médico del Perúinstacron:CMPspahttps://amp.cmp.org.pe/index.php/AMP/article/view/1081/556Copyright (c) 2020 ACTA MEDICA PERUANAinfo:eu-repo/semantics/openAccessoai:amp.cmp.org.pe:article/10812023-07-06T05:59:33Z
dc.title.none.fl_str_mv Antimicrobial therapy in severe infections
Antibioticoterapia en las infecciones graves
title Antimicrobial therapy in severe infections
spellingShingle Antimicrobial therapy in severe infections
Bisso Andrade, Aland
Antibiótico
bacteriemia
agentes antifúngicos
candidemia
sepsis
shock séptico
Anti-Bacterial Agents
bacteremia
Antifungal Agents
candidemia
sepsis
shock septic
title_short Antimicrobial therapy in severe infections
title_full Antimicrobial therapy in severe infections
title_fullStr Antimicrobial therapy in severe infections
title_full_unstemmed Antimicrobial therapy in severe infections
title_sort Antimicrobial therapy in severe infections
dc.creator.none.fl_str_mv Bisso Andrade, Aland
author Bisso Andrade, Aland
author_facet Bisso Andrade, Aland
author_role author
dc.subject.none.fl_str_mv Antibiótico
bacteriemia
agentes antifúngicos
candidemia
sepsis
shock séptico
Anti-Bacterial Agents
bacteremia
Antifungal Agents
candidemia
sepsis
shock septic
topic Antibiótico
bacteriemia
agentes antifúngicos
candidemia
sepsis
shock séptico
Anti-Bacterial Agents
bacteremia
Antifungal Agents
candidemia
sepsis
shock septic
description Sepsis is considered a public health problem because severe infections still are a major cause of death worldwide. Within the comprehensive management of the patient with severe sepsis or septic shock, the early administration of an appropriate antimicrobial regimen is one of the key strategies for survival and for reducing morbidity and mortality. In this review, we describe the antimicrobial therapy for the following conditions: severe pneumonia, urosepsis, intra-abdominal infections, serious skin and soft tissue infections, bacterial meningitis, fungal sepsis, venous catheter-related infections, and sepsis of undetermined origin. It is necessary for physicians who take care of patients with serious infections, that they must know not only the clinical manifestations of each process, but also their epidemiological characteristics, local bacterial prevalence, resistance patterns and pharmacology of available antimicrobial agents in order to make the best decisions. Both guidelines and systematic reviews are fundamental tools for the management of serious infections.
publishDate 2011
dc.date.none.fl_str_mv 2011-03-31
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://amp.cmp.org.pe/index.php/AMP/article/view/1081
url https://amp.cmp.org.pe/index.php/AMP/article/view/1081
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://amp.cmp.org.pe/index.php/AMP/article/view/1081/556
dc.rights.none.fl_str_mv Copyright (c) 2020 ACTA MEDICA PERUANA
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2020 ACTA MEDICA PERUANA
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Colegio Médico del Perú
publisher.none.fl_str_mv Colegio Médico del Perú
dc.source.none.fl_str_mv ACTA MEDICA PERUANA; Vol. 28 No. 1 (2011); 27-38
ACTA MEDICA PERUANA; Vol. 28 Núm. 1 (2011); 27-38
1728-5917
1018-8800
reponame:Acta Médica Peruana
instname:Colegio Médico del Perú
instacron:CMP
instname_str Colegio Médico del Perú
instacron_str CMP
institution CMP
reponame_str Acta Médica Peruana
collection Acta Médica Peruana
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1843344771067674624
score 12.653128
Antimicrobial therapy in severe infections
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