Cranial base chondrosarcoma: Clinicopathological analysis of a case

• Autores: Romero Yauri, José, Castillo Gutierrez, Alejandro Esteban, Castillo-Soto, Ana
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Colegio Médico del Perú
• Repositorio: Acta Médica Peruana
• Lenguaje: inglés
• OAI Identifier: oai:amp.cmp.org.pe:article/2145
• Enlace del recurso: https://amp.cmp.org.pe/index.php/AMP/article/view/2145
• Nivel de acceso: acceso abierto
• Materia: Neoplasias de la Base del Cráneo; condrosarcoma; Inmunohistoquímica; Cranial base neoplasms; Chondrosarcoma; Immunohistochemistry

Introduction:Chondrosarcoma is an unusual malignant neoplasm; cranial location is rare. Sometimes its complete resection is not possible because of vicinity of the mass to important vascular and neural structures. Clinical case: This is a 56-year old female subject who developed headache in the right side, paresthesia in the right side of her upper lip, short term memory loss, and ageusia. A magnetic resonance imaging study showed an enhanced extra-axial mass. This patient underwent complete surgical resection. The anatomopathological study showed a well differentiated chondrosarcoma of the cranial base. Conclusion: Chondrosarcoma is a malignancy with pure differentiation of the hyaline cartilage. It represents 0.15% of all intracranial tumors, and this is the second case with a cranial base location reported in Peru. Both histological characteristics and immunohistochemistry markers revealed the classic characteristics of this tumor. Therapy is given on an individualized basis.