Clinical and demographic characteristics of an adult population with neuroendocrine tumors

• Autores: Martínez Montalvo, Carlos Mauricio, Muñoz Delgado, Deiner Yivelson, Gómez Ledesma, Yeison Rodolfo, Pérez Hetting, Manuel Antonio, Vargas Calderón, María Daniela, Ordoñez Muñoz, Silvia Gabriela, Pinzón Tovar, Alejandro, Jiménez Sánchez, Héctor Conrado
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Colegio Médico del Perú
• Repositorio: Acta Médica Peruana
• Lenguaje: español
• OAI Identifier: oai:amp.cmp.org.pe:article/2058
• Enlace del recurso: https://amp.cmp.org.pe/index.php/AMP/article/view/2058
• Nivel de acceso: acceso abierto
• Materia: Carcinoma Neuroendocrino; Tumores neuroendocrinos; Neuroendocrine Carcinoma; Neuroendocrine tumors

Introduction: Neuroendocrine tumors represent a group of low-incidence neoplasms derived from neuroendocrine cells distributed throughout the body, especially the respiratory and gastrointestinal systems. Objective: To determine the clinical and sociodemographic characteristics of an adult population with neuroendocrine tumors. Materials and methods: In a descriptive cross-sectional study, 91 medical records with a diagnosis of neuroendocrine tumors confirmed by pathology were evaluated between the years 2013 and 2020. Analysis carried out in Microsoft Excel 2013 and Epi Info 7.2. Results: The mean age was 61 years, with a predominance in men (57%). The main antecedents were smoking (35%), arterial hypertension (22%), and COPD (9%). The main symptoms were abdominal pain (43%), weight loss (31%), and cough (26%). According to the origin, those of the foregut were more frequent (75%), predominantly those of the respiratory tract (39.5%). In 21.9%, the origin was unknown. Taking into account 2019 WHO classification, neuroendocrine carcinomas predominated (56%), of which the most frequent was small cell carcinoma. Among the well-differentiated (44%), low-grade (58%) followed by intermediate grade (24%) and low-grade (17%). Metastases were registered in 37% of the cases with mainly liver involvement (49%), lymph nodes (21%), and central nervous system (9%). Death occurred in 24% of cases. Conclusions: The results of the present study coincide with those reported worldwide, highlighting the predominance of tumors of pulmonary origin, as well as similar clinical symptoms according to the affected organs