Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review

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Background: Late-onset Systemic Lupus Erythematosus (SLE) is rare and affects older adults. Case report: A 71-year-old woman is reported with generalized weakness and muscle strength loss, which increased suddenly after a hemorrhagic stroke. The patient presented a torpid evolution for six months. T...

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Autores: Montoya, Karla Giovanna, Salgado-Herrera, Any, Alarcon-Ruiz, Christoper A., Lama-Valdivia, Jaime
Formato: artículo
Fecha de Publicación:2022
Institución:Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Repositorio:Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
Lenguaje:español
OAI Identifier:oai:cmhnaaa_ojs_cmhnaaa.cmhnaaa.org.pe:article/1397
Enlace del recurso:https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1397
Nivel de acceso:acceso abierto
Materia:Anciano
Polineuropatías
Lupus Eritematoso Sistémico
Lupus Erythematosus, Systemic
Aged
Polyneuropathies
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spelling Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic reviewLupus de inicio tardío neurológico asociado a accidente cerebrovascular en el adulto mayor: Reporte de caso y revisión sistemática rápidaMontoya, Karla Giovanna Salgado-Herrera, Any Alarcon-Ruiz, Christoper A.Lama-Valdivia, JaimeAncianoPolineuropatíasLupus Eritematoso SistémicoLupus Erythematosus, SystemicAgedPolyneuropathiesBackground: Late-onset Systemic Lupus Erythematosus (SLE) is rare and affects older adults. Case report: A 71-year-old woman is reported with generalized weakness and muscle strength loss, which increased suddenly after a hemorrhagic stroke. The patient presented a torpid evolution for six months. The diagnosis of late-onset SLE was confirmed with antinuclear antibodies (+) and compliance with criteria for SLE and neurolupus, with significant improvement after two weeks of treatment. We made a rapid systematic review and found few similar cases with peripheral neuropathy. Conclusion: It is necessary to consider late-onset SLE with peripheral neuropathy in older adults with muscle weakness, as an atypical clinical presentation and the need for confirmatory tests.Antecedentes: El Lupus Eritematoso Sistémico (LES) de inicio tardío es raro y afecta a adultos mayores. Reporte del caso: Se reporta a una mujer de 71 años con debilidad generalizada y pérdida de fuerza muscular, que aumentó súbitamente luego de un accidente cerebrovascular hemorrágico. La paciente presentó evolución tórpida por seis meses. El diagnóstico de LES de inicio tardío fue confirmado con anticuerpos antinucleares (+) y cumplimiento de criterios para LES y neurolupus, teniendo una mejoría significativa a las dos semanas de tratamiento. Luego de realizar una revisión sistemática rápida se encontraron pocos casos similares con neuropatía periférica. Conclusión: Es necesario considerar al LES de inicio tardío con neuropatía periférica en adultos mayores con debilidad muscular, como una presentación clínica atípica y la necesidad de exámenes confirmatorios.Cuerpo Médico del Hospital Nacional Almanzor Aguinaga Asenjo2022-10-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/139710.35434/rcmhnaaa.2022.153.1397Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo; Vol. 15 No. 3 (2022): Advance publication; 444 - 449Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo; Vol. 15 Núm. 3 (2022): Julio - Setiembre; 444 - 4492227-47312225-510910.35434/rcmhnaaa.2022.153reponame:Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjoinstname:Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjoinstacron:HNAAAspahttps://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1397/691Derechos de autor 2022 Karla Giovanna Montoya, Any Salgado-Herrera, Christoper A. Alarcon-Ruiz, Jaime Lama-Valdiviahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessoai:cmhnaaa_ojs_cmhnaaa.cmhnaaa.org.pe:article/13972024-12-02T23:41:00Z
dc.title.none.fl_str_mv Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
Lupus de inicio tardío neurológico asociado a accidente cerebrovascular en el adulto mayor: Reporte de caso y revisión sistemática rápida
title Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
spellingShingle Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
Montoya, Karla Giovanna
Anciano
Polineuropatías
Lupus Eritematoso Sistémico
Lupus Erythematosus, Systemic
Aged
Polyneuropathies
title_short Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
title_full Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
title_fullStr Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
title_full_unstemmed Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
title_sort Neurological late-onset lupus associated with cerebrovascular accident in the elderly: Case report and rapid systematic review
dc.creator.none.fl_str_mv Montoya, Karla Giovanna
Salgado-Herrera, Any
Alarcon-Ruiz, Christoper A.
Lama-Valdivia, Jaime
author Montoya, Karla Giovanna
author_facet Montoya, Karla Giovanna
Salgado-Herrera, Any
Alarcon-Ruiz, Christoper A.
Lama-Valdivia, Jaime
author_role author
author2 Salgado-Herrera, Any
Alarcon-Ruiz, Christoper A.
Lama-Valdivia, Jaime
author2_role author
author
author
dc.subject.none.fl_str_mv Anciano
Polineuropatías
Lupus Eritematoso Sistémico
Lupus Erythematosus, Systemic
Aged
Polyneuropathies
topic Anciano
Polineuropatías
Lupus Eritematoso Sistémico
Lupus Erythematosus, Systemic
Aged
Polyneuropathies
description Background: Late-onset Systemic Lupus Erythematosus (SLE) is rare and affects older adults. Case report: A 71-year-old woman is reported with generalized weakness and muscle strength loss, which increased suddenly after a hemorrhagic stroke. The patient presented a torpid evolution for six months. The diagnosis of late-onset SLE was confirmed with antinuclear antibodies (+) and compliance with criteria for SLE and neurolupus, with significant improvement after two weeks of treatment. We made a rapid systematic review and found few similar cases with peripheral neuropathy. Conclusion: It is necessary to consider late-onset SLE with peripheral neuropathy in older adults with muscle weakness, as an atypical clinical presentation and the need for confirmatory tests.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-27
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1397
10.35434/rcmhnaaa.2022.153.1397
url https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1397
identifier_str_mv 10.35434/rcmhnaaa.2022.153.1397
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1397/691
dc.rights.none.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Cuerpo Médico del Hospital Nacional Almanzor Aguinaga Asenjo
publisher.none.fl_str_mv Cuerpo Médico del Hospital Nacional Almanzor Aguinaga Asenjo
dc.source.none.fl_str_mv Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo; Vol. 15 No. 3 (2022): Advance publication; 444 - 449
Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo; Vol. 15 Núm. 3 (2022): Julio - Setiembre; 444 - 449
2227-4731
2225-5109
10.35434/rcmhnaaa.2022.153
reponame:Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
instname:Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
instacron:HNAAA
instname_str Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
instacron_str HNAAA
institution HNAAA
reponame_str Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
collection Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
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repository.mail.fl_str_mv
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