Evolution and management of the pediatric multi-systemic inflammatory syndrome associated with SARS CoV-2 infection in a pediatric ICU in Lima, Peru

• Autores: Cieza-Yamunaqué, Liliana, Rodríguez-Portilla, Ricardo, Baique-Sánchez, Michael, Coila-Paricahua, Edgar, Guerra-Ríos, Claudia, Llaque-Quiroz, Patricia, Pinedo-Torres, Isdabel Angélica
• Formato: artículo
• Fecha de Publicación: 2021
• Institución: Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Repositorio: Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Lenguaje: español
• OAI Identifier: oai:cmhnaaa_ojs_cmhnaaa.cmhnaaa.org.pe:article/1216
• Enlace del recurso: https://cmhnaaa.org.pe/ojs/index.php/rcmhnaaa/article/view/1216
• Nivel de acceso: acceso abierto
• Materia: Covid-19; Síndrome mucocutáneo linfonodular; cuidados críticos; niño; Terapéutica; Perú; lymphonodular mucocutaneous syndrome; critical care; child; Therapeutics; Peru

Background: Pediatric Multisystemic Inflammatory Syndrome (SIMP) associated with SARS CoV2 seriously affects children. Objective: To describe the symptoms, treatment and evolution of SIMP in patients of a reference Pediatric Intensive Care Unit (PICU). Findings: 18 children were identified with a mean age of 8.76 years, 50% male, all with a positive serological test. The most frequent manifestations were: fever (100%), respiratory distress (94%), abdominal pain (89%), elevated C-reactive protein (average 21.8), thrombocytopenia (50%), pathological chest X-ray (89%) and depressed myocardial contractility (61%). 72% required invasive mechanical ventilation (average 3 days) and catecholamines; 89% used corticosteroids plus immunoglobulins. The average stay in the PICU was 5.5 days. One patient died of intracerebral hemorrhage. Conclusions: SIMP in PICU is characterized by fever, respiratory distress, abdominal pain, elevated inflammatory markers, and myocardial depression. Requiring corticosteroids, immunoglobulin and ventilatory support; presenting intermediate stay and low mortality.