Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.

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Se realizó un estudio prospectivo transversal en cinco hospitales en Perú desde enero 2010 a julio 2012 para informar la incidencia, epidemiología y características clínicas de la Bordetella pertussis en niños peruanos menores de un año. Un total de 392 infantes menores de 1 año fueron admitidos con...

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Detalles Bibliográficos
Autores: Castillo, María Esther, Bada, Carlos, Del Águila, Olguita, Petrozzi-Helasvuo, Verónica, Casabona-Ore, Verónica, Reyes, Isabel, Del Valle-Mendoza, Juana
Formato: artículo
Fecha de Publicación:2015
Institución:Seguro Social de Salud
Repositorio:ESSALUD-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.essalud.gob.pe:20.500.12959/347
Enlace del recurso:https://hdl.handle.net/20.500.12959/347
http://dx.doi.org/10.1016/j.ijid.2015.10.020
Nivel de acceso:acceso abierto
Materia:Enfermedades infecciosas
Tos Ferina
Bordetella pertussis
Reacción en Cadena de la Polimerasa
Whooping cough
PCR
https://purl.org/pe-repo/ocde/ford#3.03.08
https://purl.org/pe-repo/ocde/ford#3.03.09
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dc.title.es_PE.fl_str_mv Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
title Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
spellingShingle Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
Castillo, María Esther
Enfermedades infecciosas
Tos Ferina
Bordetella pertussis
Reacción en Cadena de la Polimerasa
Bordetella pertussis
Whooping cough
PCR
https://purl.org/pe-repo/ocde/ford#3.03.08
https://purl.org/pe-repo/ocde/ford#3.03.09
title_short Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
title_full Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
title_fullStr Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
title_full_unstemmed Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
title_sort Detection of Bordetella pertussis using a PCR test in infants younger than one year old hospitalized with whooping cough in five Peruvian hospitals.
author Castillo, María Esther
author_facet Castillo, María Esther
Bada, Carlos
Del Águila, Olguita
Petrozzi-Helasvuo, Verónica
Casabona-Ore, Verónica
Reyes, Isabel
Del Valle-Mendoza, Juana
author_role author
author2 Bada, Carlos
Del Águila, Olguita
Petrozzi-Helasvuo, Verónica
Casabona-Ore, Verónica
Reyes, Isabel
Del Valle-Mendoza, Juana
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Castillo, María Esther
Bada, Carlos
Del Águila, Olguita
Petrozzi-Helasvuo, Verónica
Casabona-Ore, Verónica
Reyes, Isabel
Del Valle-Mendoza, Juana
dc.subject.es_PE.fl_str_mv Enfermedades infecciosas
Tos Ferina
Bordetella pertussis
Reacción en Cadena de la Polimerasa
topic Enfermedades infecciosas
Tos Ferina
Bordetella pertussis
Reacción en Cadena de la Polimerasa
Bordetella pertussis
Whooping cough
PCR
https://purl.org/pe-repo/ocde/ford#3.03.08
https://purl.org/pe-repo/ocde/ford#3.03.09
dc.subject.none.fl_str_mv Bordetella pertussis
Whooping cough
PCR
dc.subject.ocde.es_PE.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.03.08
https://purl.org/pe-repo/ocde/ford#3.03.09
description Se realizó un estudio prospectivo transversal en cinco hospitales en Perú desde enero 2010 a julio 2012 para informar la incidencia, epidemiología y características clínicas de la Bordetella pertussis en niños peruanos menores de un año. Un total de 392 infantes menores de 1 año fueron admitidos con un diagnóstico clínico de tos ferina, probando la B. pertussis con el test PCR o técnica de Reacción en Cadena de la Polimerasa.
publishDate 2015
dc.date.accessioned.none.fl_str_mv 2019-04-16T14:44:46Z
dc.date.available.none.fl_str_mv 2019-04-16T14:44:46Z
dc.date.issued.fl_str_mv 2015
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.citation.es_PE.fl_str_mv International Journal of Infectious Diseases. 2015; 41.
dc.identifier.issn.none.fl_str_mv ‎1201-9712
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12959/347
dc.identifier.doi.none.fl_str_mv http://dx.doi.org/10.1016/j.ijid.2015.10.020
identifier_str_mv International Journal of Infectious Diseases. 2015; 41.
‎1201-9712
url https://hdl.handle.net/20.500.12959/347
http://dx.doi.org/10.1016/j.ijid.2015.10.020
dc.language.iso.es_PE.fl_str_mv eng
language eng
dc.relation.uri.none.fl_str_mv https://www.ijidonline.com/article/S1201-9712(15)00254-4/fulltext
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.es_PE.fl_str_mv application/pdf
dc.publisher.es_PE.fl_str_mv Oficina editorial de IJID
dc.publisher.country.es_PE.fl_str_mv PE
dc.source.es_PE.fl_str_mv Seguro Social de Salud (EsSalud)
Repositorio Institucional EsSalud
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instname:Seguro Social de Salud
instacron:ESSALUD
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instacron_str ESSALUD
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reponame_str ESSALUD-Institucional
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spelling Castillo, María EstherBada, CarlosDel Águila, OlguitaPetrozzi-Helasvuo, VerónicaCasabona-Ore, VerónicaReyes, IsabelDel Valle-Mendoza, Juana2019-04-16T14:44:46Z2019-04-16T14:44:46Z2015International Journal of Infectious Diseases. 2015; 41.‎1201-9712https://hdl.handle.net/20.500.12959/347http://dx.doi.org/10.1016/j.ijid.2015.10.020Se realizó un estudio prospectivo transversal en cinco hospitales en Perú desde enero 2010 a julio 2012 para informar la incidencia, epidemiología y características clínicas de la Bordetella pertussis en niños peruanos menores de un año. Un total de 392 infantes menores de 1 año fueron admitidos con un diagnóstico clínico de tos ferina, probando la B. pertussis con el test PCR o técnica de Reacción en Cadena de la Polimerasa.Objectives: To report the incidence, epidemiology, and clinical features of Bordetella pertussis in Peruvian infants under 1 year old. Patients and methods: A prospective cross-sectional study was conducted in five hospitals in Peru from January 2010 to July 2012. A total of 392 infants under 1 year old were admitted with a clinical diagnosis of whooping cough and tested for B. pertussis by PCR. Results: The pertussis toxin and IS481 genes were detected in 39.54% (155/392) of the cases. Infants aged less than 3 months were the most affected, with a prevalence of 73.55% (114/155). The most common household contact was the mother, identified in 20% (31/155) of cases. Paroxysm of coughing (89.03%, 138/155), cyanosis (68.39%, 106/155), respiratory distress (67.09%, 104/155), and breastfeeding difficulties (39.35%, 61/155) were the most frequent symptoms reported. Conclusion: An increase in pertussis cases has been reported in recent years in Peru, despite national immunization efforts. 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