Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application

Descripción del Articulo

This research was funded by FONDECYT-CONCYTEC (grant contract number 238-2015-FONDECYT).
Detalles Bibliográficos
Autores: Aubert-Viard F., Mogrovejo-Valdivia A., Tabary N., Maton M., Chai F., Neut C., Martel B., Blanchemain N.
Formato: artículo
Fecha de Publicación:2019
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/603
Enlace del recurso:https://hdl.handle.net/20.500.12390/603
https://doi.org/10.1016/j.msec.2019.03.044
Nivel de acceso:acceso abierto
Materia:Weaving
Chitosan
Cyclodextrins
Heat treatment
Multilayers
Plastic bottles
Textiles
Antibacterial textiles
Chlorhexidine
Genipin
Layer by layer
Deposition
https://purl.org/pe-repo/ocde/ford#3.00.00
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oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/603
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
title Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
spellingShingle Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
Aubert-Viard F.
Weaving
Chitosan
Cyclodextrins
Heat treatment
Multilayers
Plastic bottles
Textiles
Antibacterial textiles
Chlorhexidine
Genipin
Layer by layer
Deposition
https://purl.org/pe-repo/ocde/ford#3.00.00
title_short Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
title_full Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
title_fullStr Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
title_full_unstemmed Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
title_sort Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application
author Aubert-Viard F.
author_facet Aubert-Viard F.
Mogrovejo-Valdivia A.
Tabary N.
Maton M.
Chai F.
Neut C.
Martel B.
Blanchemain N.
author_role author
author2 Mogrovejo-Valdivia A.
Tabary N.
Maton M.
Chai F.
Neut C.
Martel B.
Blanchemain N.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Aubert-Viard F.
Mogrovejo-Valdivia A.
Tabary N.
Maton M.
Chai F.
Neut C.
Martel B.
Blanchemain N.
dc.subject.none.fl_str_mv Weaving
topic Weaving
Chitosan
Cyclodextrins
Heat treatment
Multilayers
Plastic bottles
Textiles
Antibacterial textiles
Chlorhexidine
Genipin
Layer by layer
Deposition
https://purl.org/pe-repo/ocde/ford#3.00.00
dc.subject.es_PE.fl_str_mv Chitosan
Cyclodextrins
Heat treatment
Multilayers
Plastic bottles
Textiles
Antibacterial textiles
Chlorhexidine
Genipin
Layer by layer
Deposition
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.00.00
description This research was funded by FONDECYT-CONCYTEC (grant contract number 238-2015-FONDECYT).
publishDate 2019
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/603
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.msec.2019.03.044
dc.identifier.scopus.none.fl_str_mv 2-s2.0-85062857223
url https://hdl.handle.net/20.500.12390/603
https://doi.org/10.1016/j.msec.2019.03.044
identifier_str_mv 2-s2.0-85062857223
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Materials Science and Engineering C
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Ltd
publisher.none.fl_str_mv Elsevier Ltd
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1844883099268153344
spelling Publicationrp01192600rp01190600rp01188600rp01191600rp01187600rp01194600rp01189600rp01193600Aubert-Viard F.Mogrovejo-Valdivia A.Tabary N.Maton M.Chai F.Neut C.Martel B.Blanchemain N.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2019https://hdl.handle.net/20.500.12390/603https://doi.org/10.1016/j.msec.2019.03.0442-s2.0-85062857223This research was funded by FONDECYT-CONCYTEC (grant contract number 238-2015-FONDECYT).The aim of this work is to design a wound dressing able to release chlorhexidine (CHX) as antiseptic agent, ensuring long-lasting antibacterial efficacy during the healing. The textile nonwoven (polyethylene terephthalate) (PET) of the dressing was first modified by chitosan (CHT) crosslinked with genipin (Gpn). Parameters such as the concentration of reagents (Gpn and CHT) but also the crosslinking time and the working temperature were optimized to reach the maximal positive charges surface density. This support was then treated by the layer-by-layer (LbL) deposition of a multilayer system composed of methyl-beta-cyclodextrin polymer (PCD) (anionic) and CHT (cationic). After a thermal treatment to stabilize the LbL film, the textiles were loaded with CHX as antiseptic agent. The influence of the thermal treatment i) on the cytocompatibility, ii) on the degradation of the multilayer system, iii) on CHX sorption and release profiles and iv) on the antibacterial activity of the loaded textiles was studied.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengElsevier LtdMaterials Science and Engineering Cinfo:eu-repo/semantics/openAccessWeavingChitosan-1Cyclodextrins-1Heat treatment-1Multilayers-1Plastic bottles-1Textiles-1Antibacterial textiles-1Chlorhexidine-1Genipin-1Layer by layer-1Deposition-1https://purl.org/pe-repo/ocde/ford#3.00.00-1Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing applicationinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#20.500.12390/603oai:repositorio.concytec.gob.pe:20.500.12390/6032024-05-30 15:22:25.048http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="518cdf04-1b3c-43f7-a901-9cb4a06c8998"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Evaluation of antibacterial textile covered by layer-by-layer coating and loaded with chlorhexidine for wound dressing application</Title> <PublishedIn> <Publication> <Title>Materials Science and Engineering C</Title> </Publication> </PublishedIn> <PublicationDate>2019</PublicationDate> <DOI>https://doi.org/10.1016/j.msec.2019.03.044</DOI> <SCP-Number>2-s2.0-85062857223</SCP-Number> <Authors> <Author> <DisplayName>Aubert-Viard F.</DisplayName> <Person id="rp01192" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Mogrovejo-Valdivia A.</DisplayName> <Person id="rp01190" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Tabary N.</DisplayName> <Person id="rp01188" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Maton M.</DisplayName> <Person id="rp01191" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Chai F.</DisplayName> <Person id="rp01187" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Neut C.</DisplayName> <Person id="rp01194" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Martel B.</DisplayName> <Person id="rp01189" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Blanchemain N.</DisplayName> <Person id="rp01193" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Elsevier Ltd</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>Weaving</Keyword> <Keyword>Chitosan</Keyword> <Keyword>Cyclodextrins</Keyword> <Keyword>Heat treatment</Keyword> <Keyword>Multilayers</Keyword> <Keyword>Plastic bottles</Keyword> <Keyword>Textiles</Keyword> <Keyword>Antibacterial textiles</Keyword> <Keyword>Chlorhexidine</Keyword> <Keyword>Genipin</Keyword> <Keyword>Layer by layer</Keyword> <Keyword>Deposition</Keyword> <Abstract>The aim of this work is to design a wound dressing able to release chlorhexidine (CHX) as antiseptic agent, ensuring long-lasting antibacterial efficacy during the healing. The textile nonwoven (polyethylene terephthalate) (PET) of the dressing was first modified by chitosan (CHT) crosslinked with genipin (Gpn). Parameters such as the concentration of reagents (Gpn and CHT) but also the crosslinking time and the working temperature were optimized to reach the maximal positive charges surface density. This support was then treated by the layer-by-layer (LbL) deposition of a multilayer system composed of methyl-beta-cyclodextrin polymer (PCD) (anionic) and CHT (cationic). After a thermal treatment to stabilize the LbL film, the textiles were loaded with CHX as antiseptic agent. The influence of the thermal treatment i) on the cytocompatibility, ii) on the degradation of the multilayer system, iii) on CHX sorption and release profiles and iv) on the antibacterial activity of the loaded textiles was studied.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
score 13.364993
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