Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis
Descripción del Articulo
This work was partially supported by the Fogarty International Center/NIH (training grant numbers D43TW001140 and D43TW007393) and by the National Council for Science, Technology and Innovation of Peru (CONCYTEC).
| Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2018 |
| Institución: | Consejo Nacional de Ciencia Tecnología e Innovación |
| Repositorio: | CONCYTEC-Institucional |
| Lenguaje: | inglés |
| OAI Identifier: | oai:repositorio.concytec.gob.pe:20.500.12390/517 |
| Enlace del recurso: | https://hdl.handle.net/20.500.12390/517 https://doi.org/10.1093/cid/cix774 |
| Nivel de acceso: | acceso abierto |
| Materia: | x-ray computed tomography helminth antibody adult Article cyst (resting stage) cysticercus (cestode larva) enzyme linked immunoelectrotransfer blot female human immunoblotting latent class analysis major clinical study male molecular weight neurocysticercosis neuroimaging nuclear magnetic resonance imaging protein expression protein family serology staging Taenia solium https://purl.org/pe-repo/ocde/ford#3.00.00 |
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| dc.title.none.fl_str_mv |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis |
| title |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis |
| spellingShingle |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis Arroyo G. x-ray computed tomography helminth antibody adult Article cyst (resting stage) cysticercus (cestode larva) enzyme linked immunoelectrotransfer blot enzyme linked immunoelectrotransfer blot female female human immunoblotting latent class analysis major clinical study male molecular weight neurocysticercosis neuroimaging nuclear magnetic resonance imaging protein expression protein family serology staging Taenia solium https://purl.org/pe-repo/ocde/ford#3.00.00 |
| title_short |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis |
| title_full |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis |
| title_fullStr |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis |
| title_full_unstemmed |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis |
| title_sort |
Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis |
| author |
Arroyo G. |
| author_facet |
Arroyo G. Rodriguez S. Lescano A.G. Alroy K.A. Bustos J.A. Santivañez S. Pretell E.J. Garcia H.H. Gilman R.H. Gonzalez A.E. Tsang V.C.W. Gonzalez I. Saavedra H. Martinez M. Alvarado M. Verastegui M. Zimic M. Mayta H. Guerra C. Castillo Y. Castro Y. Lopez M.T. Gavidia C.M. Gomez L. Moyano L.M. Gamboa R. Muro C. Vilchez P. Nash T.E. Mahanty S. Noh J. Handali S. Friedland J. |
| author_role |
author |
| author2 |
Rodriguez S. Lescano A.G. Alroy K.A. Bustos J.A. Santivañez S. Pretell E.J. Garcia H.H. Gilman R.H. Gonzalez A.E. Tsang V.C.W. Gonzalez I. Saavedra H. Martinez M. Alvarado M. Verastegui M. Zimic M. Mayta H. Guerra C. Castillo Y. Castro Y. Lopez M.T. Gavidia C.M. Gomez L. Moyano L.M. Gamboa R. Muro C. Vilchez P. Nash T.E. Mahanty S. Noh J. Handali S. Friedland J. |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Arroyo G. Rodriguez S. Lescano A.G. Alroy K.A. Bustos J.A. Santivañez S. Pretell E.J. Garcia H.H. Gilman R.H. Gonzalez A.E. Tsang V.C.W. Gonzalez I. Saavedra H. Martinez M. Alvarado M. Verastegui M. Zimic M. Mayta H. Guerra C. Castillo Y. Castro Y. Lopez M.T. Gavidia C.M. Gomez L. Moyano L.M. Gamboa R. Muro C. Vilchez P. Nash T.E. Mahanty S. Noh J. Handali S. Friedland J. |
| dc.subject.none.fl_str_mv |
x-ray computed tomography |
| topic |
x-ray computed tomography helminth antibody adult Article cyst (resting stage) cysticercus (cestode larva) enzyme linked immunoelectrotransfer blot enzyme linked immunoelectrotransfer blot female female human immunoblotting latent class analysis major clinical study male molecular weight neurocysticercosis neuroimaging nuclear magnetic resonance imaging protein expression protein family serology staging Taenia solium https://purl.org/pe-repo/ocde/ford#3.00.00 |
| dc.subject.es_PE.fl_str_mv |
helminth antibody adult Article cyst (resting stage) cysticercus (cestode larva) enzyme linked immunoelectrotransfer blot enzyme linked immunoelectrotransfer blot female female human immunoblotting latent class analysis major clinical study male molecular weight neurocysticercosis neuroimaging nuclear magnetic resonance imaging protein expression protein family serology staging Taenia solium |
| dc.subject.ocde.none.fl_str_mv |
https://purl.org/pe-repo/ocde/ford#3.00.00 |
| description |
This work was partially supported by the Fogarty International Center/NIH (training grant numbers D43TW001140 and D43TW007393) and by the National Council for Science, Technology and Innovation of Peru (CONCYTEC). |
| publishDate |
2018 |
| dc.date.accessioned.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.available.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.issued.fl_str_mv |
2018 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12390/517 |
| dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1093/cid/cix774 |
| dc.identifier.scopus.none.fl_str_mv |
2-s2.0-85040550261 |
| url |
https://hdl.handle.net/20.500.12390/517 https://doi.org/10.1093/cid/cix774 |
| identifier_str_mv |
2-s2.0-85040550261 |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.none.fl_str_mv |
Clinical Infectious Diseases |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.uri.none.fl_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
| eu_rights_str_mv |
openAccess |
| rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
| dc.publisher.none.fl_str_mv |
Oxford University Press |
| publisher.none.fl_str_mv |
Oxford University Press |
| dc.source.none.fl_str_mv |
reponame:CONCYTEC-Institucional instname:Consejo Nacional de Ciencia Tecnología e Innovación instacron:CONCYTEC |
| instname_str |
Consejo Nacional de Ciencia Tecnología e Innovación |
| instacron_str |
CONCYTEC |
| institution |
CONCYTEC |
| reponame_str |
CONCYTEC-Institucional |
| collection |
CONCYTEC-Institucional |
| repository.name.fl_str_mv |
Repositorio Institucional CONCYTEC |
| repository.mail.fl_str_mv |
repositorio@concytec.gob.pe |
| _version_ |
1844883117754548224 |
| spelling |
Publicationrp00742600rp00004400rp00723600rp00749600rp00736600rp00744600rp00727600rp00672500rp00604500rp00738600rp00724600rp00748600rp00733600rp00737600rp00730600rp00731600rp00606500rp00747600rp00740600rp00725600rp00739600rp00741600rp00745600rp00729600rp00726600rp00728600rp00732600rp00746600rp00750600rp00734600rp00751600rp00743600rp00735600Arroyo G.Rodriguez S.Lescano A.G.Alroy K.A.Bustos J.A.Santivañez S.Pretell E.J.Garcia H.H.Gilman R.H.Gonzalez A.E.Tsang V.C.W.Gonzalez I.Saavedra H.Martinez M.Alvarado M.Verastegui M.Zimic M.Mayta H.Guerra C.Castillo Y.Castro Y.Lopez M.T.Gavidia C.M.Gomez L.Moyano L.M.Gamboa R.Muro C.Vilchez P.Nash T.E.Mahanty S.Noh J.Handali S.Friedland J.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2018https://hdl.handle.net/20.500.12390/517https://doi.org/10.1093/cid/cix7742-s2.0-85040550261This work was partially supported by the Fogarty International Center/NIH (training grant numbers D43TW001140 and D43TW007393) and by the National Council for Science, Technology and Innovation of Peru (CONCYTEC).Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervous system (CNS), and patients with a single viable brain cyst may be EITB negative. Nonetheless, EITB antibody banding patterns appears to be related with the expression of 3 protein families of Taenia solium, and in turn with the characteristics of NCC in the CNS (type, stage, and burden of viable cysts). Methods: We evaluated EITB antibody banding patterns and brain imaging findings of 548 NCC cases. Similar banding patterns were grouped into homogeneous classes using latent class analysis. The association between classes and brain imaging findings was assessed. Results: Four classes were identified. Class 1 (patients negative or only positive to the GP50 band, related to the protein family of the same name) was associated with nonviable or single viable parenchymal cysticerci; class 2 (patients positive to bands GP42-39 and GP24, related to the T24-42 protein family, with or without anti-GP50 antibodies) was associated with intraparenchymal viable and nonviable infections; classes 3 and 4 (positive to GP50, GP42-39, and GP24 but also responding to low molecular weight bands GP21, GP18, GP14, and GP13, related to the 8 kDa protein family) were associated with extraparenchymal and intraparenchymal multiple viable cysticerci. onclusions: ITB antibody banding patterns correlate with brain imaging findings and complement imaging information for the diagnosis of NCC and for staging NCC patients.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengOxford University PressClinical Infectious Diseasesinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/x-ray computed tomographyhelminth antibody-1adult-1Article-1cyst (resting stage)-1cysticercus (cestode larva)-1enzyme linked immunoelectrotransfer blot-1enzyme linked immunoelectrotransfer blot-1female-1female-1human-1immunoblotting-1latent class analysis-1major clinical study-1male-1molecular weight-1neurocysticercosis-1neuroimaging-1nuclear magnetic resonance imaging-1protein expression-1protein family-1serology-1staging-1Taenia solium-1https://purl.org/pe-repo/ocde/ford#3.00.00-1Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosisinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#20.500.12390/517oai:repositorio.concytec.gob.pe:20.500.12390/5172024-05-30 15:22:02.727https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="69f7a1c5-4a05-47e1-ad6f-8ff353ac5cf0"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients with Neurocysticercosis</Title> <PublishedIn> <Publication> <Title>Clinical Infectious Diseases</Title> </Publication> </PublishedIn> <PublicationDate>2018</PublicationDate> <DOI>https://doi.org/10.1093/cid/cix774</DOI> <SCP-Number>2-s2.0-85040550261</SCP-Number> <Authors> <Author> <DisplayName>Arroyo G.</DisplayName> <Person id="rp00742" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Rodriguez S.</DisplayName> <Person id="rp00004" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Lescano A.G.</DisplayName> <Person id="rp00723" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Alroy K.A.</DisplayName> <Person id="rp00749" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Bustos J.A.</DisplayName> <Person id="rp00736" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Santivañez S.</DisplayName> <Person id="rp00744" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Pretell E.J.</DisplayName> <Person id="rp00727" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Garcia H.H.</DisplayName> <Person id="rp00672" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gilman R.H.</DisplayName> <Person id="rp00604" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gonzalez A.E.</DisplayName> <Person id="rp00738" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Tsang V.C.W.</DisplayName> <Person id="rp00724" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gonzalez I.</DisplayName> <Person id="rp00748" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Saavedra H.</DisplayName> <Person id="rp00733" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Martinez M.</DisplayName> <Person id="rp00737" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Alvarado M.</DisplayName> <Person id="rp00730" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Verastegui M.</DisplayName> <Person id="rp00731" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Zimic M.</DisplayName> <Person id="rp00606" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Mayta H.</DisplayName> <Person id="rp00747" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Guerra C.</DisplayName> <Person id="rp00740" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Castillo Y.</DisplayName> <Person id="rp00725" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Castro Y.</DisplayName> <Person id="rp00739" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Lopez M.T.</DisplayName> <Person id="rp00741" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gavidia C.M.</DisplayName> <Person id="rp00745" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gomez L.</DisplayName> <Person id="rp00729" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Moyano L.M.</DisplayName> <Person id="rp00726" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gamboa R.</DisplayName> <Person id="rp00728" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Muro C.</DisplayName> <Person id="rp00732" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Vilchez P.</DisplayName> <Person id="rp00746" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Nash T.E.</DisplayName> <Person id="rp00750" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Mahanty S.</DisplayName> <Person id="rp00734" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Noh J.</DisplayName> <Person id="rp00751" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Handali S.</DisplayName> <Person id="rp00743" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Friedland J.</DisplayName> <Person id="rp00735" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Oxford University Press</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>https://creativecommons.org/licenses/by/4.0/</License> <Keyword>x-ray computed tomography</Keyword> <Keyword>helminth antibody</Keyword> <Keyword>adult</Keyword> <Keyword>Article</Keyword> <Keyword>cyst (resting stage)</Keyword> <Keyword>cysticercus (cestode larva)</Keyword> <Keyword>enzyme linked immunoelectrotransfer blot</Keyword> <Keyword>enzyme linked immunoelectrotransfer blot</Keyword> <Keyword>female</Keyword> <Keyword>female</Keyword> <Keyword>human</Keyword> <Keyword>immunoblotting</Keyword> <Keyword>latent class analysis</Keyword> <Keyword>major clinical study</Keyword> <Keyword>male</Keyword> <Keyword>molecular weight</Keyword> <Keyword>neurocysticercosis</Keyword> <Keyword>neuroimaging</Keyword> <Keyword>nuclear magnetic resonance imaging</Keyword> <Keyword>protein expression</Keyword> <Keyword>protein family</Keyword> <Keyword>serology</Keyword> <Keyword>staging</Keyword> <Keyword>Taenia solium</Keyword> <Abstract>Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervous system (CNS), and patients with a single viable brain cyst may be EITB negative. Nonetheless, EITB antibody banding patterns appears to be related with the expression of 3 protein families of Taenia solium, and in turn with the characteristics of NCC in the CNS (type, stage, and burden of viable cysts). Methods: We evaluated EITB antibody banding patterns and brain imaging findings of 548 NCC cases. Similar banding patterns were grouped into homogeneous classes using latent class analysis. The association between classes and brain imaging findings was assessed. Results: Four classes were identified. Class 1 (patients negative or only positive to the GP50 band, related to the protein family of the same name) was associated with nonviable or single viable parenchymal cysticerci; class 2 (patients positive to bands GP42-39 and GP24, related to the T24-42 protein family, with or without anti-GP50 antibodies) was associated with intraparenchymal viable and nonviable infections; classes 3 and 4 (positive to GP50, GP42-39, and GP24 but also responding to low molecular weight bands GP21, GP18, GP14, and GP13, related to the 8 kDa protein family) were associated with extraparenchymal and intraparenchymal multiple viable cysticerci. onclusions: ITB antibody banding patterns correlate with brain imaging findings and complement imaging information for the diagnosis of NCC and for staging NCC patients.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1 |
| score |
13.9061165 |
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
