Mapping of CGRP in the alpaca (Lama pacos) brainstem

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This work has been supported by the Ministerio de Educación y Ciencia (BFU2005-02241/BFI), Spain and by the CONCYTEC: PROCYT project 2006, Peru. The authors thank Ewing Rafael Duque for his technical assistance, N. Skinner for stylistic revision of the English text and Professor Gerard Tramu (Univer...

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Autores: de Souza E., Coveñas R., Yi P., Aguilar L.A., Lerma L., Andrade R., Mangas A., Díaz-Cabiale Z., Narváez J.A.
Formato: artículo
Fecha de Publicación:2008
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/725
Enlace del recurso:https://hdl.handle.net/20.500.12390/725
https://doi.org/10.1016/j.jchemneu.2008.02.004
Nivel de acceso:acceso abierto
Materia:leucine
calcitonin gene related peptide
enkephalin
alpaca
animal cell
animal experiment
article
brain mapping
brain stem
controlled study
cuneate nucleus
facial nerve nucleus
hypoglossal nucleus
immunocytochemistry
https://purl.org/pe-repo/ocde/ford#3.01.04
id CONC_5ae1827ef6e03638aa5406bced9d9f30
oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/725
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Mapping of CGRP in the alpaca (Lama pacos) brainstem
title Mapping of CGRP in the alpaca (Lama pacos) brainstem
spellingShingle Mapping of CGRP in the alpaca (Lama pacos) brainstem
de Souza E.
leucine
calcitonin gene related peptide
enkephalin
alpaca
animal cell
animal experiment
article
brain mapping
brain stem
controlled study
cuneate nucleus
facial nerve nucleus
hypoglossal nucleus
immunocytochemistry
https://purl.org/pe-repo/ocde/ford#3.01.04
title_short Mapping of CGRP in the alpaca (Lama pacos) brainstem
title_full Mapping of CGRP in the alpaca (Lama pacos) brainstem
title_fullStr Mapping of CGRP in the alpaca (Lama pacos) brainstem
title_full_unstemmed Mapping of CGRP in the alpaca (Lama pacos) brainstem
title_sort Mapping of CGRP in the alpaca (Lama pacos) brainstem
author de Souza E.
author_facet de Souza E.
Coveñas R.
Yi P.
Aguilar L.A.
Lerma L.
Andrade R.
Mangas A.
Díaz-Cabiale Z.
Narváez J.A.
author_role author
author2 Coveñas R.
Yi P.
Aguilar L.A.
Lerma L.
Andrade R.
Mangas A.
Díaz-Cabiale Z.
Narváez J.A.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv de Souza E.
Coveñas R.
Yi P.
Aguilar L.A.
Lerma L.
Andrade R.
Mangas A.
Díaz-Cabiale Z.
Narváez J.A.
dc.subject.none.fl_str_mv leucine
topic leucine
calcitonin gene related peptide
enkephalin
alpaca
animal cell
animal experiment
article
brain mapping
brain stem
controlled study
cuneate nucleus
facial nerve nucleus
hypoglossal nucleus
immunocytochemistry
https://purl.org/pe-repo/ocde/ford#3.01.04
dc.subject.es_PE.fl_str_mv calcitonin gene related peptide
enkephalin
alpaca
animal cell
animal experiment
article
brain mapping
brain stem
controlled study
cuneate nucleus
facial nerve nucleus
hypoglossal nucleus
immunocytochemistry
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.01.04
description This work has been supported by the Ministerio de Educación y Ciencia (BFU2005-02241/BFI), Spain and by the CONCYTEC: PROCYT project 2006, Peru. The authors thank Ewing Rafael Duque for his technical assistance, N. Skinner for stylistic revision of the English text and Professor Gerard Tramu (University of Bordeaux I, France) for kindly providing the CGRP antiserum.
publishDate 2008
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2008
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/725
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.jchemneu.2008.02.004
dc.identifier.scopus.none.fl_str_mv 2-s2.0-43649085616
url https://hdl.handle.net/20.500.12390/725
https://doi.org/10.1016/j.jchemneu.2008.02.004
identifier_str_mv 2-s2.0-43649085616
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Journal of Chemical Neuroanatomy
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Taylor & Francis Onlinne
publisher.none.fl_str_mv Taylor & Francis Onlinne
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
_version_ 1844883054212939776
spelling Publicationrp01816600rp01504500rp01819600rp01500500rp01817600rp01818600rp01546500rp01505500rp01503500de Souza E.Coveñas R.Yi P.Aguilar L.A.Lerma L.Andrade R.Mangas A.Díaz-Cabiale Z.Narváez J.A.2024-05-30T23:13:38Z2024-05-30T23:13:38Z2008https://hdl.handle.net/20.500.12390/725https://doi.org/10.1016/j.jchemneu.2008.02.0042-s2.0-43649085616This work has been supported by the Ministerio de Educación y Ciencia (BFU2005-02241/BFI), Spain and by the CONCYTEC: PROCYT project 2006, Peru. The authors thank Ewing Rafael Duque for his technical assistance, N. Skinner for stylistic revision of the English text and Professor Gerard Tramu (University of Bordeaux I, France) for kindly providing the CGRP antiserum.In this study, we demonstrate the presence of immunoreactive structures containing calcitonin gene-related peptide in the alpaca brainstem. This is the first time that a detailed mapping of the cell bodies and fibers containing this neuropeptide in the alpaca brainstem has been carried out using an immunocytochemical technique. Immunoreactive cell bodies and fibers were widely distributed throughout the alpaca brainstem. A high density of calcitonin gene-related peptide-immunoreactive perikarya was found in the superior colliculus, the dorsal nucleus of the raphe, the trochlear nucleus, the lateral division of the marginal nucleus of the brachium conjunctivum, the motor trigeminal nucleus, the facial nucleus, the pons reticular formation, the retrofacial nucleus, the rostral hypoglossal nucleus, and in the motor dorsal nucleus of the vagus, whereas a high density of fibers containing calcitonin gene-related peptide was observed in the lateral division of the marginal nucleus of the brachium conjunctivum, the parvocellular division of the alaminar spinal trigeminal nucleus, the external cuneate nucleus, the nucleus of the solitary tract, the laminar spinal trigeminal nucleus, and in the area postrema. This widespread distribution indicates that the neuropeptide studied might be involved in multiple functions in the alpaca brainstem.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengTaylor & Francis OnlinneJournal of Chemical Neuroanatomyinfo:eu-repo/semantics/openAccessleucinecalcitonin gene related peptide-1enkephalin-1alpaca-1animal cell-1animal experiment-1article-1brain mapping-1brain stem-1controlled study-1cuneate nucleus-1facial nerve nucleus-1hypoglossal nucleus-1immunocytochemistry-1https://purl.org/pe-repo/ocde/ford#3.01.04-1Mapping of CGRP in the alpaca (Lama pacos) brainsteminfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC20.500.12390/725oai:repositorio.concytec.gob.pe:20.500.12390/7252024-05-30 15:58:48.663http://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="0cd4e10c-5e8c-49e7-87df-08f89a006160"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Mapping of CGRP in the alpaca (Lama pacos) brainstem</Title> <PublishedIn> <Publication> <Title>Journal of Chemical Neuroanatomy</Title> </Publication> </PublishedIn> <PublicationDate>2008</PublicationDate> <DOI>https://doi.org/10.1016/j.jchemneu.2008.02.004</DOI> <SCP-Number>2-s2.0-43649085616</SCP-Number> <Authors> <Author> <DisplayName>de Souza E.</DisplayName> <Person id="rp01816" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Coveñas R.</DisplayName> <Person id="rp01504" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Yi P.</DisplayName> <Person id="rp01819" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Aguilar L.A.</DisplayName> <Person id="rp01500" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Lerma L.</DisplayName> <Person id="rp01817" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Andrade R.</DisplayName> <Person id="rp01818" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Mangas A.</DisplayName> <Person id="rp01546" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Díaz-Cabiale Z.</DisplayName> <Person id="rp01505" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Narváez J.A.</DisplayName> <Person id="rp01503" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Taylor &amp; Francis Onlinne</DisplayName> <OrgUnit /> </Publisher> </Publishers> <Keyword>leucine</Keyword> <Keyword>calcitonin gene related peptide</Keyword> <Keyword>enkephalin</Keyword> <Keyword>alpaca</Keyword> <Keyword>animal cell</Keyword> <Keyword>animal experiment</Keyword> <Keyword>article</Keyword> <Keyword>brain mapping</Keyword> <Keyword>brain stem</Keyword> <Keyword>controlled study</Keyword> <Keyword>cuneate nucleus</Keyword> <Keyword>facial nerve nucleus</Keyword> <Keyword>hypoglossal nucleus</Keyword> <Keyword>immunocytochemistry</Keyword> <Abstract>In this study, we demonstrate the presence of immunoreactive structures containing calcitonin gene-related peptide in the alpaca brainstem. This is the first time that a detailed mapping of the cell bodies and fibers containing this neuropeptide in the alpaca brainstem has been carried out using an immunocytochemical technique. Immunoreactive cell bodies and fibers were widely distributed throughout the alpaca brainstem. A high density of calcitonin gene-related peptide-immunoreactive perikarya was found in the superior colliculus, the dorsal nucleus of the raphe, the trochlear nucleus, the lateral division of the marginal nucleus of the brachium conjunctivum, the motor trigeminal nucleus, the facial nucleus, the pons reticular formation, the retrofacial nucleus, the rostral hypoglossal nucleus, and in the motor dorsal nucleus of the vagus, whereas a high density of fibers containing calcitonin gene-related peptide was observed in the lateral division of the marginal nucleus of the brachium conjunctivum, the parvocellular division of the alaminar spinal trigeminal nucleus, the external cuneate nucleus, the nucleus of the solitary tract, the laminar spinal trigeminal nucleus, and in the area postrema. This widespread distribution indicates that the neuropeptide studied might be involved in multiple functions in the alpaca brainstem.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
score 13.377223
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