Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition

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The initial development of the algorithm was funded by a Wellcome Trust Career Development Fellowship awarded to DAJM [078067/Z/05] and by the Peruvian FINCYT Proyecto de Interes Nacional [PIN 061] and CONCYTEC PROCYT awarded to MZ. The funders had no role in study design, data collection and analys...

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Detalles Bibliográficos
Autores: Alva, A, Aquino, F, Gilman, RH, Olivares, C, Requena, D, Gutierrez, AH, Caviedes, L, Coronel, J, Larson, S, Sheen, P, Moore, DAJ, Zimic, M
Formato: artículo
Fecha de Publicación:2013
Institución:Consejo Nacional de Ciencia Tecnología e Innovación
Repositorio:CONCYTEC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorio.concytec.gob.pe:20.500.12390/1121
Enlace del recurso:https://hdl.handle.net/20.500.12390/1121
https://doi.org/10.1371/journal.pone.0082809
Nivel de acceso:acceso abierto
Materia:tuberculosis
automatic diagnostics
https://purl.org/pe-repo/ocde/ford#3.03.08
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oai_identifier_str oai:repositorio.concytec.gob.pe:20.500.12390/1121
network_acronym_str CONC
network_name_str CONCYTEC-Institucional
repository_id_str 4689
dc.title.none.fl_str_mv Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
title Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
spellingShingle Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
Alva, A
tuberculosis
automatic diagnostics
automatic diagnostics
https://purl.org/pe-repo/ocde/ford#3.03.08
title_short Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
title_full Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
title_fullStr Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
title_full_unstemmed Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
title_sort Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
author Alva, A
author_facet Alva, A
Aquino, F
Gilman, RH
Olivares, C
Requena, D
Gutierrez, AH
Caviedes, L
Coronel, J
Larson, S
Sheen, P
Moore, DAJ
Zimic, M
author_role author
author2 Aquino, F
Gilman, RH
Olivares, C
Requena, D
Gutierrez, AH
Caviedes, L
Coronel, J
Larson, S
Sheen, P
Moore, DAJ
Zimic, M
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Alva, A
Aquino, F
Gilman, RH
Olivares, C
Requena, D
Gutierrez, AH
Caviedes, L
Coronel, J
Larson, S
Sheen, P
Moore, DAJ
Zimic, M
dc.subject.none.fl_str_mv tuberculosis
topic tuberculosis
automatic diagnostics
automatic diagnostics
https://purl.org/pe-repo/ocde/ford#3.03.08
dc.subject.es_PE.fl_str_mv automatic diagnostics
automatic diagnostics
dc.subject.ocde.none.fl_str_mv https://purl.org/pe-repo/ocde/ford#3.03.08
description The initial development of the algorithm was funded by a Wellcome Trust Career Development Fellowship awarded to DAJM [078067/Z/05] and by the Peruvian FINCYT Proyecto de Interes Nacional [PIN 061] and CONCYTEC PROCYT awarded to MZ. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
publishDate 2013
dc.date.accessioned.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.available.none.fl_str_mv 2024-05-30T23:13:38Z
dc.date.issued.fl_str_mv 2013
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/20.500.12390/1121
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1371/journal.pone.0082809
dc.identifier.isi.none.fl_str_mv 328735700093
url https://hdl.handle.net/20.500.12390/1121
https://doi.org/10.1371/journal.pone.0082809
identifier_str_mv 328735700093
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv PLOS ONE
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.none.fl_str_mv https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0/
dc.publisher.none.fl_str_mv PLOS
publisher.none.fl_str_mv PLOS
dc.source.none.fl_str_mv reponame:CONCYTEC-Institucional
instname:Consejo Nacional de Ciencia Tecnología e Innovación
instacron:CONCYTEC
instname_str Consejo Nacional de Ciencia Tecnología e Innovación
instacron_str CONCYTEC
institution CONCYTEC
reponame_str CONCYTEC-Institucional
collection CONCYTEC-Institucional
repository.name.fl_str_mv Repositorio Institucional CONCYTEC
repository.mail.fl_str_mv repositorio@concytec.gob.pe
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spelling Publicationrp00907500rp03152600rp00604500rp03154600rp00601500rp03157600rp03153600rp00523500rp03155600rp00526500rp03156600rp00606400Alva, AAquino, FGilman, RHOlivares, CRequena, DGutierrez, AHCaviedes, LCoronel, JLarson, SSheen, PMoore, DAJZimic, M2024-05-30T23:13:38Z2024-05-30T23:13:38Z2013https://hdl.handle.net/20.500.12390/1121https://doi.org/10.1371/journal.pone.0082809328735700093The initial development of the algorithm was funded by a Wellcome Trust Career Development Fellowship awarded to DAJM [078067/Z/05] and by the Peruvian FINCYT Proyecto de Interes Nacional [PIN 061] and CONCYTEC PROCYT awarded to MZ. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Tuberculosis control efforts are hampered by a mismatch in diagnostic technology: modern optimal diagnostic tests are least available in poor areas where they are needed most. Lack of adequate early diagnostics and MDR detection is a critical problem in control efforts. The Microscopic Observation Drug Susceptibility (MODS) assay uses visual recognition of cording patterns from Mycobacterium tuberculosis (MTB) to diagnose tuberculosis infection and drug susceptibility directly from a sputum sample in 7–10 days with a low cost. An important limitation that laboratories in the developing world face in MODS implementation is the presence of permanent technical staff with expertise in reading MODS.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengPLOSPLOS ONEinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/4.0/tuberculosisautomatic diagnostics-1automatic diagnostics-1https://purl.org/pe-repo/ocde/ford#3.03.08-1Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognitioninfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTEC#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#20.500.12390/1121oai:repositorio.concytec.gob.pe:20.500.12390/11212024-05-30 15:44:12.036https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_14cbinfo:eu-repo/semantics/closedAccessmetadata only accesshttps://repositorio.concytec.gob.peRepositorio Institucional CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="2ea74c4c-c55f-4c4e-8147-7e820c900f65"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition</Title> <PublishedIn> <Publication> <Title>PLOS ONE</Title> </Publication> </PublishedIn> <PublicationDate>2013</PublicationDate> <DOI>https://doi.org/10.1371/journal.pone.0082809</DOI> <ISI-Number>328735700093</ISI-Number> <Authors> <Author> <DisplayName>Alva, A</DisplayName> <Person id="rp00907" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Aquino, F</DisplayName> <Person id="rp03152" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gilman, RH</DisplayName> <Person id="rp00604" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Olivares, C</DisplayName> <Person id="rp03154" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Requena, D</DisplayName> <Person id="rp00601" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Gutierrez, AH</DisplayName> <Person id="rp03157" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Caviedes, L</DisplayName> <Person id="rp03153" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Coronel, J</DisplayName> <Person id="rp00523" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Larson, S</DisplayName> <Person id="rp03155" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Sheen, P</DisplayName> <Person id="rp00526" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Moore, DAJ</DisplayName> <Person id="rp03156" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Zimic, M</DisplayName> <Person id="rp00606" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>PLOS</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>https://creativecommons.org/licenses/by/4.0/</License> <Keyword>tuberculosis</Keyword> <Keyword>automatic diagnostics</Keyword> <Keyword>automatic diagnostics</Keyword> <Abstract>Tuberculosis control efforts are hampered by a mismatch in diagnostic technology: modern optimal diagnostic tests are least available in poor areas where they are needed most. Lack of adequate early diagnostics and MDR detection is a critical problem in control efforts. The Microscopic Observation Drug Susceptibility (MODS) assay uses visual recognition of cording patterns from Mycobacterium tuberculosis (MTB) to diagnose tuberculosis infection and drug susceptibility directly from a sputum sample in 7–10 days with a low cost. An important limitation that laboratories in the developing world face in MODS implementation is the presence of permanent technical staff with expertise in reading MODS.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1
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Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
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