Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics
Descripción del Articulo
Authors are very thankful to CONCYTECFONDECYT, process E041-01 (Contract number 123-2018-FONDECYT-BM-IADT/AV), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Process 305250/2019-1, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES) Finance Code 001 and P...
| Autores: | , , , , , , , , , , |
|---|---|
| Formato: | artículo |
| Fecha de Publicación: | 2021 |
| Institución: | Consejo Nacional de Ciencia Tecnología e Innovación |
| Repositorio: | CONCYTEC-Institucional |
| Lenguaje: | inglés |
| OAI Identifier: | oai:repositorio.concytec.gob.pe:20.500.12390/3163 |
| Enlace del recurso: | https://hdl.handle.net/20.500.12390/3163 https://doi.org/10.19277/bbr.18.1.256 |
| Nivel de acceso: | acceso abierto |
| Materia: | Oreochromis niloticus Allium test collagen extraction Comet assay cytotoxicity genotoxicity https://purl.org/pe-repo/ocde/ford#3.02.27 |
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| dc.title.none.fl_str_mv |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics |
| title |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics |
| spellingShingle |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics Sánchez Tuesta, Linda Cristina Oreochromis niloticus Allium test collagen extraction Comet assay Comet assay cytotoxicity cytotoxicity genotoxicity https://purl.org/pe-repo/ocde/ford#3.02.27 |
| title_short |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics |
| title_full |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics |
| title_fullStr |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics |
| title_full_unstemmed |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics |
| title_sort |
Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics |
| author |
Sánchez Tuesta, Linda Cristina |
| author_facet |
Sánchez Tuesta, Linda Cristina Reátegui Pinedo, Nataly Yahayra Salirrosas Fernández, Remigio David Morocho-Jácome, Ana Lucía Daud Sarruf, Fernanda Miliani Martinez, Renata Quevedo-León, Roberto Fiestas Jacinto, Ramiro Ayala-Jara, Carmen Rolim Baby, André Prieto Lara, Zulita Adriana |
| author_role |
author |
| author2 |
Reátegui Pinedo, Nataly Yahayra Salirrosas Fernández, Remigio David Morocho-Jácome, Ana Lucía Daud Sarruf, Fernanda Miliani Martinez, Renata Quevedo-León, Roberto Fiestas Jacinto, Ramiro Ayala-Jara, Carmen Rolim Baby, André Prieto Lara, Zulita Adriana |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Sánchez Tuesta, Linda Cristina Reátegui Pinedo, Nataly Yahayra Salirrosas Fernández, Remigio David Morocho-Jácome, Ana Lucía Daud Sarruf, Fernanda Miliani Martinez, Renata Quevedo-León, Roberto Fiestas Jacinto, Ramiro Ayala-Jara, Carmen Rolim Baby, André Prieto Lara, Zulita Adriana |
| dc.subject.none.fl_str_mv |
Oreochromis niloticus |
| topic |
Oreochromis niloticus Allium test collagen extraction Comet assay Comet assay cytotoxicity cytotoxicity genotoxicity https://purl.org/pe-repo/ocde/ford#3.02.27 |
| dc.subject.es_PE.fl_str_mv |
Allium test collagen extraction Comet assay Comet assay cytotoxicity cytotoxicity genotoxicity |
| dc.subject.ocde.none.fl_str_mv |
https://purl.org/pe-repo/ocde/ford#3.02.27 |
| description |
Authors are very thankful to CONCYTECFONDECYT, process E041-01 (Contract number 123-2018-FONDECYT-BM-IADT/AV), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Process 305250/2019-1, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES) Finance Code 001 and Programa Nacional de Pós-Doutorado (PNPD). |
| publishDate |
2021 |
| dc.date.accessioned.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.available.none.fl_str_mv |
2024-05-30T23:13:38Z |
| dc.date.issued.fl_str_mv |
2021 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12390/3163 |
| dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.19277/bbr.18.1.256 |
| url |
https://hdl.handle.net/20.500.12390/3163 https://doi.org/10.19277/bbr.18.1.256 |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.none.fl_str_mv |
Biomedical and Biopharmaceutical Research Journal |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.uri.none.fl_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| eu_rights_str_mv |
openAccess |
| rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| dc.publisher.none.fl_str_mv |
Associação Lusófona para o Desenvolvimento da investigação e Ensino em Ciências da Saúde (ALIES) |
| publisher.none.fl_str_mv |
Associação Lusófona para o Desenvolvimento da investigação e Ensino em Ciências da Saúde (ALIES) |
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reponame:CONCYTEC-Institucional instname:Consejo Nacional de Ciencia Tecnología e Innovación instacron:CONCYTEC |
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Consejo Nacional de Ciencia Tecnología e Innovación |
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CONCYTEC |
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CONCYTEC |
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CONCYTEC-Institucional |
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CONCYTEC-Institucional |
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Publicationrp08953600rp08954600rp08951600rp08962600rp08963600rp08955600rp08961600rp08952600rp08717600rp08719600rp08720600Sánchez Tuesta, Linda CristinaReátegui Pinedo, Nataly YahayraSalirrosas Fernández, Remigio DavidMorocho-Jácome, Ana LucíaDaud Sarruf, FernandaMiliani Martinez, RenataQuevedo-León, RobertoFiestas Jacinto, RamiroAyala-Jara, CarmenRolim Baby, AndréPrieto Lara, Zulita Adriana2024-05-30T23:13:38Z2024-05-30T23:13:38Z2021https://hdl.handle.net/20.500.12390/3163https://doi.org/10.19277/bbr.18.1.256Authors are very thankful to CONCYTECFONDECYT, process E041-01 (Contract number 123-2018-FONDECYT-BM-IADT/AV), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Process 305250/2019-1, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES) Finance Code 001 and Programa Nacional de Pós-Doutorado (PNPD).Obtaining new cosmetic ingredients, mainly from sustainable sources, as novel excipients or even active compounds is noteworthy for the cosmetic industry to enhance new innovative dermocosmetics. Thus, it is essential to establish the safety of these new ingredients to avoid adverse events, mainly those associated with clastogenic effects from the chemical compounds used for collagen extraction. In this study, we evaluated solutions of chemical compounds used in the collagen extraction process from tilapia skin (Oreochromis niloticus). The cytotoxic and genotoxic effects of the solutions used in the collagen extraction process were 10.0, 1.0, 0.5, and 0.1% n-butanol. Solutions were evaluated by the Allium test and the comet assay in peripheral white blood cells. The residual water from the final skin wash in the pre-treatment phase and the 0.5% lyophilized collagen extract were also investigated. The absence of cytotoxic and genotoxic activity was demonstrated in the collagen extract, despite the fact that n-butanol showed DNA damage, both in the root cells of Allium cepa and in the white blood cells of human peripheral blood. Therefore, we note the necessity to carry out genotoxicity tests to guarantee the absence of contaminants in the collagen extract for cosmetic purposes.Consejo Nacional de Ciencia, Tecnología e Innovación Tecnológica - ConcytecengAssociação Lusófona para o Desenvolvimento da investigação e Ensino em Ciências da Saúde (ALIES)Biomedical and Biopharmaceutical Research Journalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/4.0/Oreochromis niloticusAllium test-1collagen extraction-1Comet assay-1Comet assay-1cytotoxicity-1cytotoxicity-1genotoxicity-1https://purl.org/pe-repo/ocde/ford#3.02.27-1Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmeticsinfo:eu-repo/semantics/articlereponame:CONCYTEC-Institucionalinstname:Consejo Nacional de Ciencia Tecnología e Innovacióninstacron:CONCYTECTHUMBNAIL2021_Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia)....pdf.jpg2021_Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia)....pdf.jpgIM Thumbnailimage/jpeg14324https://repositorio.concytec.gob.pe/bitstreams/ef51d7ee-c8b0-f5c2-e3a7-6b778e2fa442/downloadd117b9a6a37973294624bf520600c639MD52ORIGINAL2021_Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia)....pdf2021_Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia)....pdfapplication/pdf4505019https://repositorio.concytec.gob.pe/bitstreams/f8440507-54b6-c391-4897-6b553398d9a0/downloadf1cde825a3f287d2e7f8301fb1ec4230MD51TEXT2021_Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from 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CONCYTECrepositorio@concytec.gob.pe#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="2fdf115c-4d3e-4295-8ceb-1a9827dd1a01"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Preliminary safety evaluation of n-butanol from the collagen extraction process and of collagen extract from Oreochromis niloticus (tilapia) skin oriented for dermocosmetics</Title> <PublishedIn> <Publication> <Title>Biomedical and Biopharmaceutical Research Journal</Title> </Publication> </PublishedIn> <PublicationDate>2021</PublicationDate> <DOI>https://doi.org/10.19277/bbr.18.1.256</DOI> <Authors> <Author> <DisplayName>Sánchez Tuesta, Linda Cristina</DisplayName> <Person id="rp08953" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Reátegui Pinedo, Nataly Yahayra</DisplayName> <Person id="rp08954" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Salirrosas Fernández, Remigio David</DisplayName> <Person id="rp08951" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Morocho-Jácome, Ana Lucía</DisplayName> <Person id="rp08962" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Daud Sarruf, Fernanda</DisplayName> <Person id="rp08963" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Miliani Martinez, Renata</DisplayName> <Person id="rp08955" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Quevedo-León, Roberto</DisplayName> <Person id="rp08961" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Fiestas Jacinto, Ramiro</DisplayName> <Person id="rp08952" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Ayala-Jara, Carmen</DisplayName> <Person id="rp08717" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Rolim Baby, André</DisplayName> <Person id="rp08719" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> <Author> <DisplayName>Prieto Lara, Zulita Adriana</DisplayName> <Person id="rp08720" /> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Associação Lusófona para o Desenvolvimento da investigação e Ensino em Ciências da Saúde (ALIES)</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>https://creativecommons.org/licenses/by-nc-nd/4.0/</License> <Keyword>Oreochromis niloticus</Keyword> <Keyword>Allium test</Keyword> <Keyword>collagen extraction</Keyword> <Keyword>Comet assay</Keyword> <Keyword>Comet assay</Keyword> <Keyword>cytotoxicity</Keyword> <Keyword>cytotoxicity</Keyword> <Keyword>genotoxicity</Keyword> <Abstract>Obtaining new cosmetic ingredients, mainly from sustainable sources, as novel excipients or even active compounds is noteworthy for the cosmetic industry to enhance new innovative dermocosmetics. Thus, it is essential to establish the safety of these new ingredients to avoid adverse events, mainly those associated with clastogenic effects from the chemical compounds used for collagen extraction. In this study, we evaluated solutions of chemical compounds used in the collagen extraction process from tilapia skin (Oreochromis niloticus). The cytotoxic and genotoxic effects of the solutions used in the collagen extraction process were 10.0, 1.0, 0.5, and 0.1% n-butanol. Solutions were evaluated by the Allium test and the comet assay in peripheral white blood cells. The residual water from the final skin wash in the pre-treatment phase and the 0.5% lyophilized collagen extract were also investigated. The absence of cytotoxic and genotoxic activity was demonstrated in the collagen extract, despite the fact that n-butanol showed DNA damage, both in the root cells of Allium cepa and in the white blood cells of human peripheral blood. Therefore, we note the necessity to carry out genotoxicity tests to guarantee the absence of contaminants in the collagen extract for cosmetic purposes.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication> -1 |
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Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).
