Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer

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This retrospective study evaluated the relationship between factors according to TNM clinical classification proposed by the UICC in 1987 in 122 patients with histologically confirmed breast cancer overlooking Bethlehem Hospital from 1966 to 1983. The mean age was 48.4 ± 11.9 years (range, 23-87 yea...

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Autores: Díaz Plasencia, Juan, Tantaleán Ramella, Enrique, Guzmán Gavidia, Carlos, Tuesta Salas, Enrique, Rodríguez Ascón, Faviola, Pomatanta Plasencia, Jorge
Formato: artículo
Fecha de Publicación:2015
Institución:Sociedad Peruana de Obstetricia y Ginecología
Repositorio:Revista SPOG - Revista Peruana de Ginecología y Obstetricia
Lenguaje:español
OAI Identifier:oai:ojs.spog:article/1351
Enlace del recurso:http://www.spog.org.pe/web/revista/index.php/RPGO/article/view/1351
Nivel de acceso:acceso abierto
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dc.title.none.fl_str_mv Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
Relación entre el tumor primario (T), ganglios linfático regionales (N) y metartasis a distancia (M) en el estadiaje clínico del cáncer de mama
title Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
spellingShingle Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
Díaz Plasencia, Juan
title_short Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
title_full Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
title_fullStr Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
title_full_unstemmed Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
title_sort Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancer
dc.creator.none.fl_str_mv Díaz Plasencia, Juan
Tantaleán Ramella, Enrique
Guzmán Gavidia, Carlos
Tuesta Salas, Enrique
Rodríguez Ascón, Faviola
Pomatanta Plasencia, Jorge
author Díaz Plasencia, Juan
author_facet Díaz Plasencia, Juan
Tantaleán Ramella, Enrique
Guzmán Gavidia, Carlos
Tuesta Salas, Enrique
Rodríguez Ascón, Faviola
Pomatanta Plasencia, Jorge
author_role author
author2 Tantaleán Ramella, Enrique
Guzmán Gavidia, Carlos
Tuesta Salas, Enrique
Rodríguez Ascón, Faviola
Pomatanta Plasencia, Jorge
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv

dc.description.none.fl_txt_mv This retrospective study evaluated the relationship between factors according to TNM clinical classification proposed by the UICC in 1987 in 122 patients with histologically confirmed breast cancer overlooking Bethlehem Hospital from 1966 to 1983. The mean age was 48.4 ± 11.9 years (range, 23-87 years). The fifth decade was the most affected (36.1%) and 62 patients (50.8%) were premenopausal. The TE medium was 12.5 months (range, 12 days to 10 years), the most frequent symptoms were breast lump (95.1%), breast tenderness (40.9%), skin redness (13.1%) and haematological Nipple discharge (6.5%) . Clinical signs were diagnosis: tumor (99.1%), axillary lymph node (46.7%), retraction of the nipple (33.6%) and orange peel (18.8%). The most frequently committed neoplasia left breast (55.8%) than the right (44.2%); and it was located in the CSE in 54.1% of cases, 21.3% CSI, CIE 8.2%, the entire breast in 7.4%, the central region at 5.7% and 3.3% IIC . Of the 122 patients, 3 (2.5%) were in EC-0, 8 (6.6%) in CD-I, 33 (27.0%) in EC II-A, 34 (27.9%) in EC II-B, 12 ( 9.8%) in EC III-A, 17 (13.9%) in EC III-B and 15 (12.3%) in EC IV. Fifteen patients (12.3%) presented MAD, the most frequent sites: lung (53.3%), pleura (26.6%), supraclavicular lymph node (33.3%), peritoneum (13.3) and bone (6.6%). There were statistically significant direct relationship between T and N (p <0.001) and the incidence of M (p <0.001). There was also significant direct relationship between N and M (p <0.002). Conclude that there is correlation between T. N and M, and clinical staging is important because it helps to plan treatment, it is prognostic value and facilitates the exchange of information between various centers.
Este estudio retrospectivo evalúa la relación entre los factores TNM de acuerdo a la clasificación clínica propuesta por la UICC en 1987 en 122 pacientes con diagnóstico histológico de cáncer de mama vistas en el Hospital de Belén entre 1966 a 1983. La edad media fue 48.4±11.9 años (rango, 23 a 87 años). La quinta década fue la más afectada (36.1%) y 62 pacientes (50.8%) fueron premenopáusicas. El TE medio fue 12.5 meses (rango, 12 días a 10 años), los síntomas más frecuentes fueron nódulo mamario (95.1%), mastalgia (40.9%), enrojecimiento de piel (13.1%) y secreción hemática por pezón (6.5%). Los signos clínicos al diagnóstico fueron: tumor (99.1%), adenopatía axilar (46.7%), retracción del pezón (33.6%) y piel de naranja (18.8%). La neoplasia comprometió con más frecuencia la mama izquierda (55.8%) que la derecha (44.2%); y ésta se localizó en el CSE en el 54.1% de los casos, CSI en el 21.3%, CIE en el 8.2%, toda la mama en el 7.4%, la región central en el 5.7% y en el CII en el 3.3%. De las 122 pacientes, 3 (2.5%) estuvieron en EC-0, 8 (6.6%) en EC-I, 33 (27.0%) en EC II-A, 34 (27.9%) en EC II-B, 12 (9.8%) en EC III-A, 17 (13.9%) en EC III-B y 15 (12.3%) en EC IV. Quince pacientes (12.3%), presentaron MAD, siendo las localizaciones más frecuentes: pulmón (53.3%), pleura (26.6%), ganglio supraclavicular (33.3%), peritoneo (13.3) y huesos (6.6%). Hubo relación directa estadísticamente significativa entre el T y el N (p<0.001) y la incidencia de M (p<0.001). Además hubo relación directa significativa entre el N y M (p<0.002). Concluimos que hay correlación entre el T. N y M, y que el estadiaje clínico es importante porque ayuda a planificar el tratamiento, es de valor pronóstico y facilita el intercambio de información entre diversos centros.
description This retrospective study evaluated the relationship between factors according to TNM clinical classification proposed by the UICC in 1987 in 122 patients with histologically confirmed breast cancer overlooking Bethlehem Hospital from 1966 to 1983. The mean age was 48.4 ± 11.9 years (range, 23-87 years). The fifth decade was the most affected (36.1%) and 62 patients (50.8%) were premenopausal. The TE medium was 12.5 months (range, 12 days to 10 years), the most frequent symptoms were breast lump (95.1%), breast tenderness (40.9%), skin redness (13.1%) and haematological Nipple discharge (6.5%) . Clinical signs were diagnosis: tumor (99.1%), axillary lymph node (46.7%), retraction of the nipple (33.6%) and orange peel (18.8%). The most frequently committed neoplasia left breast (55.8%) than the right (44.2%); and it was located in the CSE in 54.1% of cases, 21.3% CSI, CIE 8.2%, the entire breast in 7.4%, the central region at 5.7% and 3.3% IIC . Of the 122 patients, 3 (2.5%) were in EC-0, 8 (6.6%) in CD-I, 33 (27.0%) in EC II-A, 34 (27.9%) in EC II-B, 12 ( 9.8%) in EC III-A, 17 (13.9%) in EC III-B and 15 (12.3%) in EC IV. Fifteen patients (12.3%) presented MAD, the most frequent sites: lung (53.3%), pleura (26.6%), supraclavicular lymph node (33.3%), peritoneum (13.3) and bone (6.6%). There were statistically significant direct relationship between T and N (p <0.001) and the incidence of M (p <0.001). There was also significant direct relationship between N and M (p <0.002). Conclude that there is correlation between T. N and M, and clinical staging is important because it helps to plan treatment, it is prognostic value and facilitates the exchange of information between various centers.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-14
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info:eu-repo/semantics/publishedVersion

format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://www.spog.org.pe/web/revista/index.php/RPGO/article/view/1351
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url http://www.spog.org.pe/web/revista/index.php/RPGO/article/view/1351
identifier_str_mv 10.31403/rpgo.v39i1351
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dc.publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
publisher.none.fl_str_mv Sociedad Peruana de Obstetricia y Ginecología
dc.source.none.fl_str_mv Revista Peruana de Ginecología y Obstetricia; Vol. 39, Núm. 14 (1993); 34-37
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spelling Relationship between the primary tumor (T), regional lymph nodes (N) and metartasis distance (M) in the clinical staging of breast cancerRelación entre el tumor primario (T), ganglios linfático regionales (N) y metartasis a distancia (M) en el estadiaje clínico del cáncer de mamaDíaz Plasencia, JuanTantaleán Ramella, EnriqueGuzmán Gavidia, CarlosTuesta Salas, EnriqueRodríguez Ascón, FaviolaPomatanta Plasencia, JorgeThis retrospective study evaluated the relationship between factors according to TNM clinical classification proposed by the UICC in 1987 in 122 patients with histologically confirmed breast cancer overlooking Bethlehem Hospital from 1966 to 1983. The mean age was 48.4 ± 11.9 years (range, 23-87 years). The fifth decade was the most affected (36.1%) and 62 patients (50.8%) were premenopausal. The TE medium was 12.5 months (range, 12 days to 10 years), the most frequent symptoms were breast lump (95.1%), breast tenderness (40.9%), skin redness (13.1%) and haematological Nipple discharge (6.5%) . Clinical signs were diagnosis: tumor (99.1%), axillary lymph node (46.7%), retraction of the nipple (33.6%) and orange peel (18.8%). The most frequently committed neoplasia left breast (55.8%) than the right (44.2%); and it was located in the CSE in 54.1% of cases, 21.3% CSI, CIE 8.2%, the entire breast in 7.4%, the central region at 5.7% and 3.3% IIC . Of the 122 patients, 3 (2.5%) were in EC-0, 8 (6.6%) in CD-I, 33 (27.0%) in EC II-A, 34 (27.9%) in EC II-B, 12 ( 9.8%) in EC III-A, 17 (13.9%) in EC III-B and 15 (12.3%) in EC IV. Fifteen patients (12.3%) presented MAD, the most frequent sites: lung (53.3%), pleura (26.6%), supraclavicular lymph node (33.3%), peritoneum (13.3) and bone (6.6%). There were statistically significant direct relationship between T and N (p <0.001) and the incidence of M (p <0.001). There was also significant direct relationship between N and M (p <0.002). Conclude that there is correlation between T. N and M, and clinical staging is important because it helps to plan treatment, it is prognostic value and facilitates the exchange of information between various centers.Este estudio retrospectivo evalúa la relación entre los factores TNM de acuerdo a la clasificación clínica propuesta por la UICC en 1987 en 122 pacientes con diagnóstico histológico de cáncer de mama vistas en el Hospital de Belén entre 1966 a 1983. La edad media fue 48.4±11.9 años (rango, 23 a 87 años). La quinta década fue la más afectada (36.1%) y 62 pacientes (50.8%) fueron premenopáusicas. El TE medio fue 12.5 meses (rango, 12 días a 10 años), los síntomas más frecuentes fueron nódulo mamario (95.1%), mastalgia (40.9%), enrojecimiento de piel (13.1%) y secreción hemática por pezón (6.5%). Los signos clínicos al diagnóstico fueron: tumor (99.1%), adenopatía axilar (46.7%), retracción del pezón (33.6%) y piel de naranja (18.8%). La neoplasia comprometió con más frecuencia la mama izquierda (55.8%) que la derecha (44.2%); y ésta se localizó en el CSE en el 54.1% de los casos, CSI en el 21.3%, CIE en el 8.2%, toda la mama en el 7.4%, la región central en el 5.7% y en el CII en el 3.3%. De las 122 pacientes, 3 (2.5%) estuvieron en EC-0, 8 (6.6%) en EC-I, 33 (27.0%) en EC II-A, 34 (27.9%) en EC II-B, 12 (9.8%) en EC III-A, 17 (13.9%) en EC III-B y 15 (12.3%) en EC IV. Quince pacientes (12.3%), presentaron MAD, siendo las localizaciones más frecuentes: pulmón (53.3%), pleura (26.6%), ganglio supraclavicular (33.3%), peritoneo (13.3) y huesos (6.6%). Hubo relación directa estadísticamente significativa entre el T y el N (p<0.001) y la incidencia de M (p<0.001). Además hubo relación directa significativa entre el N y M (p<0.002). Concluimos que hay correlación entre el T. N y M, y que el estadiaje clínico es importante porque ayuda a planificar el tratamiento, es de valor pronóstico y facilita el intercambio de información entre diversos centros.Sociedad Peruana de Obstetricia y Ginecología2015-07-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://www.spog.org.pe/web/revista/index.php/RPGO/article/view/135110.31403/rpgo.v39i1351Revista Peruana de Ginecología y Obstetricia; Vol. 39, Núm. 14 (1993); 34-372304-51322304-5124reponame:Revista SPOG - Revista Peruana de Ginecología y Obstetriciainstname:Sociedad Peruana de Obstetricia y Ginecologíainstacron:SPOGspahttp://www.spog.org.pe/web/revista/index.php/RPGO/article/view/1351/1303info:eu-repo/semantics/openAccess2021-05-03T15:50:17Zmail@mail.com -
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