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replication process » application process (Expander búsqueda), realization process (Expander búsqueda), application processes (Expander búsqueda)
dna replication » data replication (Expander búsqueda), a replication (Expander búsqueda), una replicacion (Expander búsqueda)
replication process » application process (Expander búsqueda), realization process (Expander búsqueda), application processes (Expander búsqueda)
dna replication » data replication (Expander búsqueda), a replication (Expander búsqueda), una replicacion (Expander búsqueda)
1
artículo
Publicado 2008
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Directed evolution allows us to explore protein functionalities not required in the natural environment. It mimics natural genetic processes and selective pressures. This approach is used when the molecular basis is not completely understood and rational design is a difficult task. This approach consists of serial cycles of consecutive diversification and selection which eventually lead to the accumulation of beneficial mutations. Here are presented two cases where directed evolution is used to modify two different proteins: Taq polymerase, enzyme used for DNA extension in PCR, and the LacI repressor protein which regulates gene expression on E.coli.
2
artículo
Publicado 2008
Enlace
Enlace
Directed evolution allows us to explore protein functionalities not required in the natural environment. It mimics natural genetic processes and selective pressures. This approach is used when the molecular basis is not completely understood and rational design is a difficult task. This approach consists of serial cycles of consecutive diversification and selection which eventually lead to the accumulation of beneficial mutations. Here are presented two cases where directed evolution is used to modify two different proteins: Taq polymerase, enzyme used for DNA extension in PCR, and the LacI repressor protein which regulates gene expression on E.coli.
3
artículo
Publicado 2020
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The study of the complex ultracellular processes of nucleic acids is a subject debated as a scientific argument in favor of Intelligent Design (ID). The objective of this work was to analyze some molecular processes of the nucleic acids that suggest the confirmation of the ID theory, through the technique of documentary content analysis. First, the chemical structure of DNA and the combination of nitrogenous bases reflects that the genetic information of each created being is an original mixture of nitrogenous bases that makes each individual unique in the history of the world. Secondly, by studying the processes of DNA replication and repair, it is observed that each enzyme fulfills its function in a coordinated and organized manner avoiding the occurrence of errors and, should this occur, the cell has had very fine repair mechanisms. that correct these alterations in the best possible ...
4
artículo
Publicado 2020
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The study of the complex ultracellular processes of nucleic acids is a subject debated as a scientific argument in favor of Intelligent Design (ID). The objective of this work was to analyze some molecular processes of the nucleic acids that suggest the confirmation of the ID theory, through the technique of documentary content analysis. First, the chemical structure of DNA and the combination of nitrogenous bases reflects that the genetic information of each created being is an original mixture of nitrogenous bases that makes each individual unique in the history of the world. Secondly, by studying the processes of DNA replication and repair, it is observed that each enzyme fulfills its function in a coordinated and organized manner avoiding the occurrence of errors and, should this occur, the cell has had very fine repair mechanisms. that correct these alterations in the best possible ...
5
tesis de grado
Publicado 2024
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El proceso de replicación y reparación del ADN es crucial en la generación de mutaciones y la evolución del ADN. Utilizando la distribución de Boltzmann para un conjunto canónico, se puede calcular la probabilidad de ingreso de nucleótidos libres al sitio de replicación, afectada por factores como la energía potencial molecular, la abundancia de nucleótidos, la secuencia de ADN cercana, y la temperatura. Estos factores incluyen la energía de los puentes de hidrógeno y las interacciones electrostáticas. Este enfoque permite calcular las probabilidades de mutaciones ocurridas durante la replicación del ADN, ofreciendo información sobre la acumulación de nucleótidos a lo largo de la evolución. Hay dos métodos de estudio: simulaciones computacionales y aproximaciones analíticas. Nuestro estudio previo incluyó una simulación de Monte Carlo que estimó energías y predijo...
