The present report evaluated the consumption characteristics of Rituximab in the Rheumatology department of Hospital Víctor Lazarte Echegaray - EsSalud. A descriptive, cross - sectional and retrospective study of drug use was carried out, including patients hospitalized in the Rheumatology Service during January - December 2016. The Prescribed Daily Dose System (PDD) was used as a unit of measurement of consumer spending included in this period. The study had a total of 60 patients, with demographic data corresponding to 26.67% of the consumption of Rituximab in female patients, with ages ranging from 61 to 70 years, in the case of the% of consumption units of Rituximab showed an increase in the last three months with percentages 13.19% of consumption units, which is why the average consumption expressed in daily dose prescribed DDP is 2 158.92 DDP, presenting an annual consumption cost...