|Summary:||Antimicrobial resistance is a growing threat to public health. Globally Staphylococci are recognized as pathogens that cause nosocomial and community infections.1-3 The inducible clindamycin resistant (D Phenotype present) is further complicated when methicillin resistance is added, leaving aside the use of alternative antibiotics such as those belonging to MLS B group (macrolides, lincosamides and streptogramins B). These mechanisms can be detected by the D-Test and using a cefoxitin disk during Kirby–Bauer test 4-6. The purpose of this document is to determine the frequency of Staphylococcus aureus and coagulase-negative resistant Staphylococci to methicillin and inducible clindamycin, where isolates received by the Referential Laboratory of La Libertad. Samples where taken from patients from three hospitals in La Libertad. Each sample where analized with disk diffusion method with cefoxitin and oxacillin, also the D-test standardized according to CLSI guidelines. In the results of inducible resistance to Clindamycin , two ( 4.1 % ) isolates were coagulase negative Staphylococcus spp . while 7 isolates ( 21.2 %) were coagulase positive Staphylococcus aureus . And the results of methicillin resistance showed 20 ( 40.8 % ) isolates were Staphylococcus coagulase-negative while 19 isolates ( 57.6 %) were coagulase positive Staphylococcus aureus . They result simultaneous insulation resistance where 1 (2%) was also obtained Staphylococcus coagulase-negative and 6 isolates ( 18.2 %) of coagulase positive Staphylococcus aureus.|
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